Epi may cause restlessness, throbbing headache, tremor, and palpitations; these effects rapidly subside with rest, quiet, recumbency, and reassurance. More serious reactions include cerebral hemorrhage and cardiac arrhythmias. The use of large doses or the accidental, rapid intravenous injection of Epi may result in cerebral hemorrhage from the sharp rise in blood pressure. Ventricular arrhythmias may follow the drug's administration. Epi may induce angina in patients with coronary artery disease. Use of Epi generally is contraindicated in patients receiving nonselective b receptor—blocking drugs, since its unopposed actions on vascular a1 receptors may lead to severe hypertension and cerebral hemorrhage.
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Are Headaches Taking Your Life Hostage and Preventing You From Living to Your Fullest Potential? Are you tired of being given the run around by doctors who tell you that your headaches or migraines are psychological or that they have no cause that can be treated? Are you sick of calling in sick because you woke up with a headache so bad that you can barely think or see straight?