Toxicity

Untoward effects of ephedrine include hypertension and insomnia. Tachyphylaxis may occur with repetitive dosing. Usual or higher-than-recommended doses may cause adverse cardiovascular effects in individuals with underlying cardiovascular disease. Herbal preparations containing ephedrine (ma huang, ephedra) are widely utilized; these preparations vary in their content of ephedrine; thus, their use may lead to inadvertent consumption of dangerously high doses of ephedrine and its isomers. Because of this, the FDA has banned the sale of dietary supplements containing ephedra in the U.S.

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