patient compliance medication errors rate and extent of absorption body size and composition distribution in body fluids binding In plasma and tissues rate of elimination
physiological variables pathological factors genetic factors interaction with other drugs development of tolerance drug-receptor interaction functional state placebo effects
FIGURE 5-1 Factors that determine the relationship between prescribed drug dosage and drug effect.
indicated in Figure 5-1. Therapeutic success and safety result from integrating evidence of efficacy and safety with knowledge of the individual factors that determine response in a given patient.
Was this article helpful?
Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...