Caffeine and benzodiazepines

Benzodiazepines are widely used for the treatment of anxiety and insomnia as well as a variety of other disorders. In most countries they are available on medical prescription. Problems of dependence and abuse have been recognized for some time, although the dependence potential of these drugs remains a matter of contention.14 In addition to their anxiolytic and hypnotic effects, benzodiazepines produce sedation, muscle relaxation, and cognitive and psychomotor impairment. A number of studies...