M

M28 peptidase family, 3 Macro-structural pathology of brain, 99 Magnetic resonance spectroscopy detection of

NAA in vivo, 210 Magnetic Resonance User Interface, 220-221 Magnetoencephalography, 227 Marker of nueronal injury in neurodegenerative disease, 245 MBP see Cytoplasmic myelin basic protein MCAO see Middle cerebral artery occlusion Measures of neuron-vascular system interactions, 97 Mechanism of axonal damage, 205 Medial temporal lobe, 250

MEG see Magnetoencephalography Mesial temporal sclerosis, 259 Metabolic connection of NAA with NAAG, 100

Metabolic modeling of NAA-synthesis, 270 Metabolism of NAA, 49

Asp-NAT precursor of, 50 Metabolite concentrations in human brain tumors, 194 Metabolites choline-containing of, 253, 258 Metabotropic glutamate receptor, 23, 98, 102 Metabotropic glutamate receptor antagonist, 324

Metallo-exopeptidase enzyme, 322 Metastatic prostate cancer cells, 3 Method for Assay of NAA-Synthase, 133 Methylamines glycerophosphorylcholine, 116 mGluR antagonist, 347 mGLUR family, 3 mGluR3, 3

Michaelis-Menten constant, 69-70 Microcirculatory activity of NAAG, 104 Microdialysis probes of, 333 Middle cerebral artery occlusion, 333 Mini citric acid cycle, 59 Missense mutations, 168 Mitochondria toxin 3-nitropropionic acid, 60 Mitochondrial encephalopathy, 28, 282 Mitochondrial enzyme complexes in MS

lesions, 205 Molecular genetic studies of CD, 146 Molecular size of native Asp-NAT, 54 Molecular studies of GCPII, 3 Molecular water pump, 101 Monitoring neuronal integrity in ALS, 283 Monoclonal antibody, 2 Motor neuron disease ALS, 279 MR Spectroscopic Imaging in chronic alcohol abuse, 257 MRI tissue segmentation of, 247 MRUI see Magnetic Resonance User Interface MS see Multiple sclerosis MTL see Medial temporal lobe MTL NAA reductions in, 250 MTS see Mesial temporal sclerosis Multiple sclerosis, 59, 203-214 Murine model of CD, 151 Muscle stretch reflexes of, 281 Mutational analysis of ASPA gene in non

Jewish patients with CD, 165-171 MWP see Molecular water pump

MWP osmoregulatory activity, 103 Myelin lipid synthesis during CNS

development, 22, 132, 147, 150, 152 Myelin lipid synthesis study in CD mice, 150 Myelin protein synthesis, 147 Myelin synthesis, 67, 147 Myelinated axons in MS non-lesion white matter, 212 Myelinogenesis, 38 Myoinositol, 118

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