O

O-2A progenitor, 28-29, 35 O-2A progenitor lineage, 36, 39-41 Observation of drug effect by MRS, 282 Occipito-parietal NAA, 226 Oligodendrocyte, 35

maturation of, 30 survival of, 30 Oligodendrocyte amidohydrolase II, 99 Oligodendrocyte cell lysates, 181 Oligodendrocyte markers, 180 Oligodendrocyte progenitor cells, 208 Oligodendroglial development of, 180 ONFL see Optic nerve fiber layer OPCs see Oligodendrocyte progenitor cells Optic nerve fiber layer, 293 Optic neuropathy, 67 Optic tectum of, 297 Oral creatine supplementation of, 283 Organic efflux pathway, 118 Organic osmolyte, 116, 119-120, 122-123 Organic osmolyte pathway, 118 Osmolyte efflux pathway, 118 Osmotic brain shrinkage, 120 Osmotic buffering capacity by brain tissue, 118 Osmotic demyelination, 120 Osmotic gradients, 117 Osmotically obligated water, 117 Osmotransductory elements, 118 Over-expression of Spi1 transcription factor, 180

Oxidative damage to mitochondrial DNA, 205 Oxidative phosphorylation, 60 Oxygen-dependent phosphorescence quenching method, 98

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