The dose of dextromethorphan in children over the age 12 years is 30 mg every six to eight hours up to a maximum dose of 120 mg/24 hours. The adult recommended dose of memantine is 5 mg/24 hours, up to a maximum dose of 20 mg/24 hours. Future studies are needed to demonstrate the efficacy and safety of botulinum toxins for pediatric tension headache and other complementary therapies of magnesium, riboflavin, feverfew, and butterbur.112[V]
Table 44.6 Anticonvulsants: recommended oral dosing.
Carbamazepine 5-10mg/kg/24 hours divided into two doses; incremental increase of 10mg/kg/24 hours per week; maximum dose for children over the age of 12 years is 1.6-2.4 g/24 hours Oxcarbazepine For children over the age of 12 years, dose is 300-600 mg/24 hours; maximum dose 900-2400 mg/24 hours
Phenytoin 2-3 mg/kg divided into two to three doses per day, incremental increase of 0.5 mg/kg every 3-4 weeks;
maximum dose 5mg/kg per day (1000 mg per day) Valproic acid 5-15 mg/kg administered in a single night-time dose or three divided doses per day; incremental increase of
5-10mg/kg every 5-7 days; maximum dose 60mg/kg/day Gabapentin 5-10 mg/kg administered either once, twice, or three times a day; maximum dose 2400-3600 mg/24 hours
Lamotrigine 0.15-0.6 mg/kg/24 hours administered in a single night-time dose or twice-a-day divided dose; slow incremental increase every 2 weeks Levetiracetam 10 mg/kg/24 hours, prescribed in twice-a-day divided doses
Topiramate 1-3 mg/kg/24 hours; maximum dose 600 mg/24 hours
Zonisamide 2-4 mg/kg/24 hours; maximum dose 400 mg/24 hours
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Are Headaches Taking Your Life Hostage and Preventing You From Living to Your Fullest Potential? Are you tired of being given the run around by doctors who tell you that your headaches or migraines are psychological or that they have no cause that can be treated? Are you sick of calling in sick because you woke up with a headache so bad that you can barely think or see straight?