Factor Iv Movement Disorders And Dystrophy

Motor and movement disorders29 occur in as many as 95 percent of patients with CRPS30 and include weakness, bradykinesia, dystonia, myoclonus, and tremor. The pathophysiology appears to be of central origin when studied with functional magnetic resonance imaging (fMRI). It is difficult to measure, but activity monitors are likely more accurate that questionnaires.31,32

The picture is complicated because it has been shown that both immobility and disuse can affect motor function. Such changes might not be specific for CRPS and probably represent interactions between peripheral, spinal, and supraspinal mechanisms. It will be necessary to determine which of the motor abnormalities are generated by which particular pathologic process.

Unfortunately, there are no prospective studies of the cause of motor or movement disorders, or adequate studies of physical therapies or pharmacotherapies.

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