Key Learning Points

• Complex regional pain syndrome (CRPS) is a pain syndrome diagnosed clinically, not in the laboratory.

• CRPS occurs in the extremities and limbs.

• The prevalence and incidence of CRPS in communities is not known.

• Clinical diagnosis is made with four factors.

• Sensory changes include hyperalgesia and allodynia.

• Vasomotor changes include asymmetrical vasodilatation and vasoconstriction.

• Sudomotor changes include asymmetrical sweating.

• Edema is variably present.

• Movement disorders include tremor, weakness, and dystonia.

• Treatment is by multidisciplinary functional restoration.

• Pain relief by any modality may be required to facilitate functional restoration.

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