A suggested approach to the analysis of pain in MS is outlined in Box 24.1. It is intended to encourage the clinician to consider the pathophysiologic basis of the pain before considering which treatment modalities are most appropriate.Pains of primary neurogenic origin are divided into paroxysmal and nonparoxysmal. Paroxysmal pains may be more likely to respond to anticonvulsant drugs, whereas ongoing central pains may be more likely to respond to other groups of drugs such as anti-depressants and N-methyl-D-aspartic acid (NMDA) receptor antagonists, and in some cases opioids.
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Are Headaches Taking Your Life Hostage and Preventing You From Living to Your Fullest Potential? Are you tired of being given the run around by doctors who tell you that your headaches or migraines are psychological or that they have no cause that can be treated? Are you sick of calling in sick because you woke up with a headache so bad that you can barely think or see straight?