Phenol injections

Phenol injected perineurally on to mixed motor/sensory or motor nerves results in patchy demyelination of those nerves with a slowing of nerve conduction and a resulting decrease in spasticity.24' 58[III] Phenol can be moderately useful in focal spasticity. Whereas BoNT-A affects the individual muscle into which it is injected, phenol affects all muscles supplied by the injected nerve (Figure 33.5). The main disadvantage of phenol is the relatively high rate of late dysesthesia in the sensory distribution of the injected nerve. Phenol injected intravascularly can cause seizures, and if injected intramuscularly can lead to the development of sterile abscess.

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