Between 4 and 25 percent of school-age children complain of abdominal pain severe enough to interfere with daily activities.118[IV], 119[V], 120[IV] There appears to be an increase in prevalence in children aged four to six years and again in early adolescence,121[IV], 122[IV] with a higher prevalence in females, particularly after the age of 12 years.123[V] There is also a higher prevalence of FAP in locations with more social stressors,119[V], 124[IV]

indicating a strong psychosocial component. The majority of children with FAP probably have IBS and many children with abdominal pain without the hallmark symptom of altered bowel habit may develop this over time (for review, see Ref. 125).

Between 30 and 60 percent of these children will likely experience symptom remission.123[V], 126[V] Long-term follow-up studies have noted, however, that children with FAP are more likely to report abdominal pain several years after evaluation than healthy controls127[V]and may be at greater risk of developing psychiatric disorders.128 [V] The continuation of pain in children with FAP is associated with psychological distress,129[IV] family members with irritable bowel syndrome,130[IV] and high levels of healthcare utilization.131[II]

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