■ Thyroid hormone

■ Guaifenesin

■ Dehydroepiandrosterone (APS, 2005)

It is not uncommon to use a combination of medications to treat the various symptoms of FMS (Mease et al., 2009). The patient may be using pregabalin, duloxetine, or milnacipran for pain, along with a medication such as cyclobenzaprine as a muscle relaxant and to help promote sleep. When combining medications, use only one from a class, to avoid undesirable additive effects. For example, if you combine two drugs that boost serotonin levels, there is the potential for a serotonin syndrome to develop (Mease et al., 2009).

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