Info

antispasmodic—baclofen

5 mg tid

10-20 mg tid

benzodiazepine—diazepam

1 mg bid

2-10 mg bid-qid

Abbreviations: bid, twice daily; hs, at bedtime; tid, three times a day; qid, four times a day. Source: From American Pain Society, 2008.

Abbreviations: bid, twice daily; hs, at bedtime; tid, three times a day; qid, four times a day. Source: From American Pain Society, 2008.

Although there is no indication that these medications relax skeletal muscles, they are commonly used for spasm and muscle tightness (APS, 2008). After 1-2 weeks, the action of the medication shifts to a central activity rather than skeletal muscle activity (APS, 2008). The most common side effect of this group of medications is sedation. If they are being used concomitantly with an opioid analgesics, the sedative effect is cumulative. There is the potential for abuse in patients who are predisposed to this problem, so intermittent or short-term use is advised.

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