Figure 3. o-Nitrobenzyl-based linkers. Reference numbers indicate citations for application of these linkers in combinatorial chemistry.


The conditions for the photolytic cleavage to mediate release of the products are highly dependent on the nature of the linker, so that a general procedure cannot be outlined. It is therefore recommended that the specific conditions for each individual linker be identified in the pertinent literature reference.

A straightforward synthesis of the linker unit 111 applied in [105] was reported recently (Scheme 49) [106],

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