Homeopathic Remedies for Cystitis

UTI Be Gone By Sherry Han

UTI Be Gone by Sherry Han is a simple e-book that describes how you can eliminate urinary tract infection quickly and naturally. The report will show you how to almost immediately stop the pain caused by UTI and how to cure it with literally no side effects. UTI Be Gone takes people step-by-step through the process of learning how to get rid of symptoms of urinary tract infection easily. With the program, people will learn how to get immediate relief from endless pain caused by urinary tract infection. The program also reveals to users secrets to prevent this disease from coming back. Sherry Han will show people how she got rid of this disease within a few weeks. Since Sherry Han released the program, she has received many positive comments from customers regarding their success.

Uti be gone Natural Urinary Tract Infection Cure Summary


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HBO for Radiation Induced Hemorrhagic Cystitis

Level II (non-randomized) evidence of effect is available supporting the efficacy of HBO for the treatment of severe radiation-induced hemorrhagic cystitis refractory to conventional measures. The largest study describes 40 patients treated for 20 sessions of HBO.40 A total of 37 of the 40 patients showed marked and durable (up to 5 years) reductions in bleeding frequency, including need for blood transfusions, and no adverse effects were reported. A consecutive series of 20 patients treated between 1989 and 1992 reported improvement of hematuria in 90 of cases.41 Similar experiences based on smaller patient numbers are available.41-45 No adverse effects of HBO were reported in any of these studies.

Interstitial cystitis

At present, there is no agreed upon etiology or pathophysiology for interstitial cystitis (IC). The only defining pathology is the presence of mucosal ulcers or glomer-ulations'' (small submucosal petechial hemorrhages) viewed cystoscopically after hydrodistension (sustained distension of the bladder). The presence of Hunner's (mucosal) ulcers, so named after the first clinician to describe them, separates IC patients into those with ulcerative versus nonulcerative types. Glomerulations are not unique to IC, but occur in other forms of cystitis (e.g. radiation cystitis). Theories related to the development of IC have centered around four primary hypotheses Prevalence of IC is estimated to be 2 in 10,000.60 It has a female to male ratio of 10 1 although some are proposing that in males it may have a higher prevalence but is given the diagnosis of prostatitis. Patients with IC are 10-12 times more likely to report childhood bladder problems than the general population. Although a...

Is It Interstitial Cystitis Diagnostic Distinctions in Reduced Bladder Capacity

Summary This article addresses the questions involved in the diagnostic distinctions between interstitial cystitis (IC) and other causes of reduced bladder capacity. Topics include difficulties in diagnosing IC the physiology of bladder sensation an historical review of IC clinical terminology used, including sensory urgency, motor urgency, bladder pain, maximum cystometric capacity, and bladder compliance the role of urodynamic testing differential diagnosis, including bladder cancer and carcinoma in situ (CIS), radiation cystitis, cyclophosphamide cystitis, detrusor instability, malakoplakia, schistosomiasis, tuberculous cystitis, and eosinophilic cystitis the diagnostic approach and how the NIH defines IC. An algorithm summarizing the work-up of suspected IC is included. 3 figures. 1 table. 17 references.

Painful bladder syndrome interstitial cystitis

Painful bladder syndrome (PBS alternatively known as bladder pain syndrome) is a descriptive diagnosis that has been recently advocated for use on an international level as descriptive of a complex of urologic complaints including pain 59 . Thought to be an early form of the disorder interstitial cystitis (IC), there is an expectation that a majority of patients with PBS might have a common etiology. Notably, IC has no agreed etiology, pathophysiology or treatment and nor does the less defined PBS. The prevalence of IC is estimated to be 2 in 10,000 with a female to male ratio of 10 1. Patients with IC are 10-12 times more likely to report childhood bladder problems than the general population 60 . IC is frequently associated with other chronic disorders such as inflammatory bowel disease, systemic lupus erythematosus, irritable bowel syndrome, sensitive skin, fibromyalgia and allergies 61 . Interstitial cystitis does have a defining pathology in that the diagnosis, as defined by a...

O Antibacterial Sulfonamides

Today, there are a few sulfonamides (Table 6.7) and especially sulfonamide-trimethoprim combinations that are used extensively for opportunistic infections in patients with AIDS.107 A primary infection that is treated with the combination is PCP. The sulfonamide-trimethoprim combination can be used for treatment and prophylaxis. Additionally, cerebral toxoplasmosis can be treated in active infection or prophylactically. Urinary tract infections and burn ther-apy107-111 round out the list of therapeutic applications. The sulfonamides are drugs of choice for a few other types of infections, but their use is quite limited in modern antimicrobial chemotherapy.107-111 Treatment and prophylaxis of Pneumocystis carinii pneumonia Treatment and prophylaxis of cerebral toxoplasmosis First attack of urinary tract infection

O Newer Antibiotics

Citrobacter Species Treated With Unasyn

Aztreonam for injection is indicated for the treatment of infections caused by susceptible Gram-negative microorganism, such as urinary tract infections (complicated and uncomplicated), including pyelonephritis and cystitis (initial and recurrent) caused by E. coli, K. pneumoniae, P. mirabilis, P. aeruginosa, E. cloacae, K. oxytoca, Citrobacter sp., and S. marcescens. Aztreonam is also indicated for lower respiratory tract infections, including pneumonia and bronchitis caused by E. coli, K. pneumoniae, P. aeruginosa, H. influenzae, P. mirabilis, S. marcescens, and Enterobacter species. Aztreonam is also indicated for septicemia caused by E. coli, K. pneumoniae, P. aeruginosa, P. mirabilis, S. marcescens, and Enterobacter spp. Other infections responding to aztreonam include skin and skin structure infections, including those associated with postoperative wounds and ulcers and burns. These may be caused by E. coli, P. mirabilis, S. marcescens, Enterobacter species, P. aeruginosa, K....

Nonhuman animal models

Utilized in more than one laboratory.2 The recent past has seen a development of models that approximate physiological and behavioral responses similar to that of human visceral pain. One of the earliest models, the chemically induced writhing model in rodents, is produced by injecting irritant chemicals into the peritoneal cavity. This model has found less utility with the development of other models since the intraperitoneal injections did not selectively activate specific viscera, frequently yielded false positives when used to screen potential analgesic drugs, and are ethically questionable as they are associated with a persistent stimulus from which the animal cannot escape. Current models of visceral pain are more likely to utilize mechanical (e.g. distending) stimuli of controllable duration or chemical stimuli applied directly to relevant targets, thus permitting selectivity with respect to site of stimulation. Balloon distension of hollow organs, principally along the...

Inflammation as a mechanism

A potent modifier of behavioral, neuronal, autonomic, and motor responses to visceral stimulation in experimental models inflammation has been commonly used to produce visceral hypersensitivity. The presence of inflammation in visceral structures frequently, but not universally, leads to reports of pain and sensitivity to mechanical and chemical stimuli. Cystitis, esophagitis, gastritis, duodenitis, ileitis, colitis, and proctitis all have evidence of mucosal inflammatory changes, as a hallmark finding. However, profound inflammatory changes of the mucosal lining, such as occurs with ulcerative colitis, may present with nonpainful, bloody stools. More subtle than the histologically identifiable alterations in cell distribution are the biochemical changes that indicate a low level of chronic inflammation. Alterations in measures of oxidative stress have been observed in several hypersensitivity disorders, such as fibromylagia64 and chronic fatigue syndrome,65 and form a basis for...

Handling Increased Seizures

Seizures are predicted to decrease after initiation of the diet, and often they do. However, some patients derive marked benefit from the diet but later have an increase in seizures again. When a child who had been doing well once more experiences seizures, the question is always Why In searching for an answer, we immediately ask whether the child has an infection. As with any epilepsy, the threshold for seizures is lower during an infection and will return to a higher level when the infection disappears. It is always prudent to look for sore throats, ear infections, or urinary tract infection, as well as common viruses.

Bladder painbladder pain syndrome

There is disagreement over the terminology for pain perceived to be associated with the bladder. In the 1980s a conference of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) agreed criteria to ensure that the groups of patients enrolled in research studies would be relatively similar 9 . These criteria defined interstitial cystitis (IC) by exclusion with bladder pain, urgency The International Continence Society defined a painful bladder syndrome in 2002 11 and the European Association of Urology defined the bladder pain syndrome 12 . In a recent response (2007) to patient support groups, the ESSIC stated The name Interstitial Cystitis (IC) has been under debate for several years. Originally, IC was synonymous with Hunner's lesion of the bladder, but has subsequently expanded to be used in an undefinable population of patients with bladder pain. The ESSIC went on to emphasize The International Continence Society (ICS) published a report of definitions in...

Irritable bowel syndrome

IBS has exacerbations and spontaneous resolution of pains and so open trials initiated when the patient presents with an exacerbation can easily demonstrate the effectiveness of virtually any therapy. Placebo rates of 40-70 percent have been quoted.83 Unlike chronic pancreatitis or interstitial cystitis, procedural treatments have not been a major component of therapy because, by definition of the disease, there is no structural pathology to treat. Controlled

Chronic prostatitischronic pelvic pain syndrome

Chronic prostatitis chronic pelvic pain syndrome (CP CPPS) is defined as pain attributed to the prostate in the absence of identifiable pathology and has often been referred to as prostatodynia. Hallmark features consist of persistent complaints of urinary urgency, dysuria, poor urinary flow, and perineal discomfort without evidence of bacteria or white blood cells in prostatic fluids. It serves as a male-specific corollary to interstitial cystitis in that it has similar symptomatology, is a diagnosis of exclusion, and has a presumed site of pain generation. Infectious, inflammatory, neurological, and referred gastro-enterological etiologies of the pain need to be ruled out. Cystoscopic findings of interstitial cystitis have been found in males with the diagnosis of prostatodynia.61 Wesselmann et al.98 have suggested that interstitial cystitis, CP CPPS (male), and vulvodynia (female) may all be variations of a generalized disorder of the epithelium of the urogenital sinus. To further...

Peripheral nervous system

In particular, anandamide induces a modest contractile response in guinea pig isolated bronchus that is dependent upon the activation of vanilloid receptors on airway sensory nerves (Tucker et al., 2001). Intravenous bolus injection of anandamide evoked a TRPV1 dependent stimulatory effect on pulmonary C-fiber terminals (Lin and Lee, 2002). Anandamide (2-AG) stimulates not only pulmonary neurons but also intestinal primary sensory neurons via TRPV1 to release SP, probably resulting in enteritis (Mcvey et al., 2003). Similar to the situation in the spinal cord, in the bladder anandamide at lower concentrations inhibited (TRPV1 mediated) neuropeptide release in a CB1 dependent manner, while higher concentrations increased neuropeptide release. Moreover, intravesical instillation of anandamide increased c-fos expression in the spinal cord, which was reduced by capsazepine or by resiniferatoxin pretreatment. These results suggest that anandamide, through activation of TRPV1, contributes...

Miscellaneous Agents For Chemoprevention

1,2-Dithiol-3-thiones, reported constituents of cruciferous vegetables, are five-membered cyclic sulfur-containing compounds with antioxidant, chemotherapeutic, and chemoprotective activities. In this context, oltipraz, which was originally developed as an antischistosomal agent, was found to protect against chemically induced carcinogens in the lung, stomach, colon, and urinary bladder in animals.33 Its utility as a cancer chemopreventive agent is thought to depend on the induction of enzymes involved in Phase II xenobiotic detoxification.34 Polycyclic aromatic hydrocarbons, N-nitrosamines, and other compounds produce electrophilic carcinogenic metabolites. Thus, the fungal toxic secondary metabolite aflatoxin B1 (AFB1) may contaminate food and by epoxydation of a furane double bond by a P450 cytochrome (Fig. 13.5) give carcinogenic compounds that are inactivated by glutathione addition catalyzed by glutathione S (GSH)-transferase (see Section 2.1 of Chapter 11). Oltipraz stimulates...

Visceral Hypersensitivity Disorders

With an increased sophistication of testing related to visceral disorders, there may prove to be identifiable markers or imaging studies that allow for a reduced reliance on subjective reports of sensation. An example of this comes from the painful bladder disorder, interstitial cystitis (IC). In general, the urothelium of patients with the nonulcerative form of IC appears normal on routine cystoscopic and microscopic examination. It takes a highly sophisticated analysis to discern any quantitative differences between the tissues of IC patients and normal healthy controls such that most measures have been deemed to be of little use in diagnosis. However, when the urothelium of IC patients is examined using a scanning electron microscope, defects in the urothelial surface and tight junctions are common5 and a laboratory marker for a factor that suppresses urothelial cell proliferation may prove diagnostic for the disorder.6 Until similar subtleties of evaluation become routine, the...

Conditions which may benefit from topical TCA

Dysuria urinary frequency The use of a topical TCA for urinary frequency and dysuria requires some explanation. In those who have to intermittently self-catheterize their bladders, dysuria and frequency can complicate repeated catheterization. If a TCA is applied to the tip of the urinary catheter, then these complications can be reduced.

Clinical Use Of Vasopressin Peptides

V1 receptor-mediated therapeutic applications are based on the rationale that V1 receptors cause contraction of GI and vascular smooth muscle. V1 receptor-mediated contraction of GI smooth muscle has been used to treat postoperative ileus and abdominal distension and to dispel intestinal gas before abdominal roentgenography to avoid interfering gas shadows. V1 receptor-mediated vasoconstriction of the splanchnic arterial vessels reduces blood flow to the portal system and thereby attenuates pressure and bleeding in esophageal varices. Although endoscopic variceal banding ligation is the treatment of choice for bleeding esophageal varices, V1 receptor agonists have been used emergently until endoscopy can be performed. Simultaneous administration of nitroglycerin with V1 receptor agonists may attenuate the cardiotoxic effects of V1 agonists while enhancing their beneficial splanchnic effects. Also, V1 receptor agonists have been used during abdominal surgery in patients with portal...

Botanical Nomenclature Ever Evolving

Urinary tract antiseptic used primarily for the treatment of bladder infections. Uva ursi contains a compound known as arbutin that is considered to be at least partially responsible for its medicinal activity. Several species and subspecies of uva ursi contain arbutin however, at least one subspecies, Arctostaphylos uva-ursi subspecies stipitata, reportedly does not contain arbutin and therefore may not be medicinally equivalent to other varieties. The herbal products industry does not generally include the botanical authority

Solvents Not Widely Used for Topical Preparations

Dimethylsulphoxide is a universal solvent but can cause itching erythema and uticaria when applied to skin. However, it has been used medicinally in bladder instillations (at 50 in water) for interstitial cystitis, and is a vehicle for idoxuridine for herpes infections (though is of little value). Together with acetone, DMSO is a class 3 solvent under the FDA guidance, not known as a human health hazard at levels normally expected in pharmaceuticals and which can thus be limited by appropriate GMP practices.

Vaccinium macrocarpon Aiton

Cranberry fruit and its juice are primarily used in the Western herb market for the treatment and prevention of bladder infections. Although cranberry juice cocktail has been most frequently studied, cranberry powder and powdered concentrates are common ingredients in herbal supplements used for supporting a healthy urinary system. With widespread cultivation and familiarity of the fruits, adulteration is not evident, though there are very detailed quality criteria for cranberry fruits.


Several meta-analyses and evidence-based reviews suggest that antidepressants are useful in mitigating pain associated with neuropathy (Collins et al. 2000, Saarto and Wiffen 2007), headache (Tomkins et al. 2001), fibromyalgia (Arnold et al. 2000, O'Malley et al. 2000), and irritable bowel syndrome (Jackson et al. 2000, Lesbros-Pantoflickova et al. 2004). Although antidepressants are advocated for use in other chronic pain syndromes, e.g., rheumatologic pain conditions, chronic pelvic pain, interstitial cystitis, and oro-facial pain (Kelada and Jones 2007, Onghena and Van Houdenhove 1992, Reiter 1998), these assertions are not often based on a solid foundation of empirical work. In fact, in some of these conditions, e.g., chronic pelvic pain and interstitial cystitis, there are few randomized controlled trials with small sample sizes upon which such recommendations are based (Onghena and Van Houdenhove 1992, Sharav et al. 1987, Stones et al. 2007, Van Ophoven et al. 2004).

Basic Science

Visceral pain is often poorly localized and thus specific diagnoses are often difficult. Conditions treated can vary from cancer-related organ involvement, mesenteric ischemia syndromes, interstitial cystitis, urge incontinence, chronic pancreatitis, and many others. Human study to date on SCS for visceral pain is minimal. Khan et al. reported a case series of nine patients with chronic pancreatitis and other conditions which were improved with thoracic SCS.54 V Kapural and colleagues16 recently described a small series of patients with chronic visceral pelvic pain who were helped with SCS.16 V The use of selective stimulation of sacral roots for interstitial cystitis55 and the description of retrograde percutaneous approaches to the sacral roots56 has improved the technical access to stimulation. Visceral pain appears to be a promising area of future applications for stimulation techniques. Postherpetic neuralgia (PHN) is a syndrome of persistent (> six months...


While bone marrow and mucosal toxicities occur predictably and acutely, other organ toxicities may occur after prolonged or high-dose use these effects can appear after months or years, and may be irreversible and even lethal. All alkylating agents can cause pulmonary fibrosis, usually several months after treatment. In high-dose regimens, particularly those employing busulfan or BCNU, vascular endothelial damage may precipitate veno-occlusive disease (VOD) of the liver, an often-fatal side effect that may be reversed by the investigational drug defibrotide. After multiple cycles of therapy, the nitrosoureas and ifosfamide may lead to renal failure. Cyclophosphamide and ifosfamide release a nephrotoxic and urotoxic metabolite, acrolein, which causes a severe hemorrhagic cystitis in high-dose regimens, this side effect can be prevented by coadministration of 2-mercaptoethanesulfonate (mesna or mesnex), which conjugates acrolein. Ifosfamide in high doses for transplant causes a chronic,...


Treatment of chronic orchialgia forms a correlate to the disease entity of interstitial cystitis (Box 40.5) with numerous treatments proposed for a disease of unknown but presumably localized etiology. Traditional pain management has started with anti-inflammatories and or antibiotics. Surgical procedures including epididymectomy,

Abdominal Pain

Abdominal pain due to organic disease accounts for less than 10 of the cases of recurrent abdominal pain (RAP). Genitourinary and gastrointestinal disorders are the most common organic causes of RAP. Recurrent urinary tract infection and hydronephrosis or obstructive uropathy can present with abdominal pain. Eventually, abnormal urinalysis and pyuria will focus attention to the underlying problem. Hemolytic uremic syndrome is the most common cause of renal failure in children (Jernigan and Waldo 1994).

Symptoms And Signs

Classically, urethral syndrome presents with irritative lower urinary tract symptoms - dysuria, suprapubic discomfort, urinary frequency, and dyspareunia.101'103 Voiding dysfunction such as stranguria, the slow and painful discharge of urine, may occur. A careful physical examination should be performed to evaluate for possible structural causes of pain. The urethra should be evaluated for discharge, tenderness, or a mass suggestive of a urethral diverticulum or Skene's cyst.


This is a symptom complex characterized by pelvic pain, urinary urgency, urinary frequency, and nocturia.104 Symptoms of dyspareunia and perimenstrual exacerbation with negative laboratory studies are consistent with both interstitial cystitis (IC) and urgency frequency syn-drome.105 The National Institutes of Health (NIH) Consensus Criteria from 1988 for the diagnosis of IC includes at least two of the following pain on bladder filling relieved by emptying pain in the suprapubic, pelvic, urethral, vaginal, or perineal region glomerulations on endoscopy or decreased compliance on cystometro-gram.106 Symptoms that do not meet IC criteria can be termed painful bladder syndrome'' and are probably a variant of interstitial cystitis.


Lilac Pink Herb is the dried aerial part of Dianthus suptrhus L. or Dtanthus ckinensh L. (Fam. Caryophyilaceae). Action To relieve dysuria. and to stimulate menstrual discharge. Indications Urinary infection and urolithiasis with difficult painful urination or hematuria amenorrhea. Dosage 9 15g.

Concluding Remarks

Diseases that result from mutations in the genes that encode GPCRs represent a large and growing unmet medical need, with current therapies often insufficient to treat associated symptoms and underlying molecular defects. Pharmacological chaperones represent an alternative therapeutic approach aimed at restoring activity to mutant proteins that, although harbor molecular defects, are often functionally competent but not trafficked to their appropriate cellular location to carry out their intended physiological function. Compelling evidence for the utility of this approach has been provided in vitro, in vivo, and in the clinic for several diseases that result from mutations in Class A GPCRs. Importantly, restoration of activity for diseases with both autosomal recessive and autosomal dominant modes of inheritance highlights the ability of this approach to correct both loss-of-function and gain-of-function mutations. In order to exert their beneficial effects on receptor stability and...


The clinical toxicity of vincristine is mostly neurological. The more severe neurological manifestations may be avoided or reversed either by suspending therapy or reducing the dosage upon occurrence of motor dysfunction. Severe constipation may be prevented by a prophylactic program of laxatives and hydrophilic (bulk-forming) agents and usually is a problem only with doses above 2 mg m2. Alopecia occurs in 20 of patients given vincristine however, it is always reversible, frequently without cessation of therapy. Although less common than with vinblastine, leukopenia may occur with vincristine, and thrombocytopenia, anemia, polyuria, dysuria, fever, and GI symptoms have been reported occasionally. The syndrome of inappropriate secretion of antidiuretic hormone occasionally has occurred during vincristine therapy. In view of the rapid action of the vinca alkaloids, it is advisable to prevent hyperuricemia by the administration of allopurinol.

Alkyl Sulfonates

The toxic effects of busulfan are related to its myelosuppressive properties prolonged throm-bocytopenia may occur. Occasional patients experience nausea, vomiting, and diarrhea. Long-term use leads to impotence, sterility, amenorrhea, and fetal malformation. Rarely, patients develop asthenia and hypotension. High-dose busulfan causes VOD of the liver in up to 10 of patients, as well as seizures, hemorrhagic cystitis, alopecia, and cataracts. The coincidence of VOD and hepatotoxicity is increased by its coadministration with drugs that inhibit CYPs, including imidazoles and metronidazole, possibly by inhibition of the clearance of busulfan and or its toxic metabolites.


Deferoxamine causes a number of allergic reactions, including pruritus, wheals, rash, and anaphylaxis. Other adverse effects include dysuria, abdominal discomfort, diarrhea, fever, leg cramps, and tachycardia. Occasional cases of cataract formation have been reported. Deferox-amine may cause neurotoxicity during long-term, high-dose therapy for transfusion-dependent thalassemia major both visual and auditory changes have been described. A pulmonary syndrome has been associated with high-dose (10-25 mg kg h) deferoxamine therapy tachypnea, hypoxemia, fever, and eosinophilia are prominent manifestations. Contraindications to the use of defer-oxamine include renal insufficiency and anuria during pregnancy, the drug should be used only if clearly indicated.