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Control Diabetes Diabetes + SDI

Figure 3 GSH levels in sciatic nerve of control and diabetic rats treated with or without ARI (A) or SDI (B) (mean ± SD, n = 8-12).

Control Diabetes Diabetes + SDI

Figure 3 GSH levels in sciatic nerve of control and diabetic rats treated with or without ARI (A) or SDI (B) (mean ± SD, n = 8-12).

diabetic rats further progressed with the SDI treatment (p < 0.03 vs. untreated diabetics)

Nerve GSH levels in control and diabetic rats treated with/without ARI and SDI are presented in Fig. 3, A and B. GSH levels were decreased by 23.4% and 37.6% in 3-week and 6-week diabetic rats vs. corresponding controls (p < 0.002 and <0.001, respectively). The decrease in 6-week diabetic rats was completely corrected by the ARI treatment (p < 0.001 vs. untreated diabetics), whereas the decrease in 3-week diabetic rats further progressed with the SDI treatment (p < 0.02 vs. untreated diabetics).

Antioxidative defense enzyme activities in control and diabetic rats treated with/without DL-a-lipoic acid are presented in Table 4. SOD, catalase,

Table 4 Antioxidative Enzyme Activities in the Sciatic Nerve of Control and 6-Week Diabetic Rats Treated With/Without DL-a-Lipoic Acid (LA) (nmol/mg protein per min, 11 = 5-8).

Control Diabetic Diabetic + LA

Table 4 Antioxidative Enzyme Activities in the Sciatic Nerve of Control and 6-Week Diabetic Rats Treated With/Without DL-a-Lipoic Acid (LA) (nmol/mg protein per min, 11 = 5-8).

Control Diabetic Diabetic + LA

Diabetes 2

Diabetes 2

Diabetes is a disease that affects the way your body uses food. Normally, your body converts sugars, starches and other foods into a form of sugar called glucose. Your body uses glucose for fuel. The cells receive the glucose through the bloodstream. They then use insulin a hormone made by the pancreas to absorb the glucose, convert it into energy, and either use it or store it for later use. Learn more...

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