Case Studies

In recent years, PK/PD modeling has developed from an empirical descriptive discipline into a mechanistic science that can be applied at all stages of drug development. Preclinical PK/PD studies may prompt a series of important mechanistic studies to explore the relationship between plasma concentrations and the resulting effect on a biomarker in later stages of clinical drug development. The application of PK/PD modeling to preclinical pharmacology studies may help to provide information on drug effects and actions that would be difficult to obtain in human subjects. As such, preclinical and clinical PK/PD studies constitute a scientific basis for rational drug discovery and development. The following preclinical and clinical cases studies are presented to demonstrate how modeling techniques have improved the overall understanding of PK/PD relationship of biomarkers.

Project Management Made Easy

Project Management Made Easy

What you need to know about… Project Management Made Easy! Project management consists of more than just a large building project and can encompass small projects as well. No matter what the size of your project, you need to have some sort of project management. How you manage your project has everything to do with its outcome.

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