Case Study 3 Clinical Modeling of Brain D2 Receptor Occupancy Plasma Concentration Relationships with a Novel Antipsychotic

PK/PD modeling using functional imaging methodology such as positronemission tomography (PET) may be a very useful tool for early clinical development of antipsychotic compounds, especially in suggesting initial doses for further clinical studies. The purpose of this study was to assess PK/PD relationships of YKPi358 to guide decisions for further clinical study designs. YKPi358 is a novel serotonin (5-HT2A) and dopamine (D2) antagonist that

Drug administration

Project Management Made Easy

Project Management Made Easy

What you need to know about… Project Management Made Easy! Project management consists of more than just a large building project and can encompass small projects as well. No matter what the size of your project, you need to have some sort of project management. How you manage your project has everything to do with its outcome.

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