Conclusions

Biomarker research is greatly advanced by good-quality annotated collections of tissues, or biobanks. Biobanks raise issues that stretch from evaluation of the benefits and risks of research through to the complexity of informed consent for collections for which the research purposes and methods cannot be described in advance. This range of ethical and organizational challenges is not managed adequately by the rules, guidelines, and bureaucracies of research ethics. Part of the problem is that current research ethics leaves too much for the individual participant to assess before the relevant information is available. But many other aspects of biobanks have to do with how benefits and risks are defined, achieved, and shared, particularly those that are likely to apply to groups of individuals with inherited risks, or those classified as having risks or as being more amenable to treatment than others. These challenges raise important issues of equity and justice. They also highlight tradeoffs between research efficiency and benefits, privacy and individual control over personal information, and tissue samples. These issues are not resolvable by appeal to an existing set of rules or ethical framework to which all reasonable people agree. Inevitably, governance decisions related to biobanks will need to find a way to create legitimate policy and institutions. The political approach of deliberative democracy may hold the most promise for well-i nformed and representative input into trustworthy governance of biobanks and related research into biomarkers.

Project Management Made Easy

Project Management Made Easy

What you need to know about… Project Management Made Easy! Project management consists of more than just a large building project and can encompass small projects as well. No matter what the size of your project, you need to have some sort of project management. How you manage your project has everything to do with its outcome.

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