Protein Microarrays

In the context of the discovery of disease-associated molecules, protein micro-arrays can be thought of as miniaturized dot blots or highly multiplexed enzyme-linked immunosorbent assays (ELISAs) for serology, and highly multiplexed sedimentation, co-i mmunoprecipitation assays, or enzyme function assays for protein biochemistry. They allow data collection from hundreds of parallel interaction studies in an area the size of a single well of a 96-well ELISA plate. To achieve this type of miniaturization, the chemistry of the surface being used for spotting the proteins is important. Reagents can be coated onto activated plastics or glass to accommodate the deposition and subsequent binding of the protein onto the surface. Some examples of the chemistries used to bind proteins to the substrates are described below.

Project Management Made Easy

Project Management Made Easy

What you need to know about… Project Management Made Easy! Project management consists of more than just a large building project and can encompass small projects as well. No matter what the size of your project, you need to have some sort of project management. How you manage your project has everything to do with its outcome.

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