Biopharmaceutics Classification System

The BCS classification system is used to categorize drugs and serves to help anticipate whether drugs will have bioavailability bioequivalence problems. BCS classifies drugs according to their solubility and permeability. A drug is considered to have high solubility if drug substance at the highest dose strength for an immediate release formulation can be dissolved in lt 250 mL of water over a pH range of 1-7.5. A high permeability drug is one that has either complete intestinal absorption fa...