Preface

Drug discovery is complicated and yet rewarding in many ways. We have come to appreciate that drug discovery is possible when we are constantly making important and timely decisions for synthesis of superior compounds that have the potential for being a safe and an effective drug. Drug metabolism and pharmacokinetics play an integral role in this process.

Drug Metabolism and Pharmacokinetics Quick Guide is intended for broad readership for those working or interested in drug discovery from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics and toxicology. It provides, for the first time, a completely integrated look at multiple aspects of ADME sciences (absorption, distribution, metabolism, and excretion) in a summary format that is clear, concise, and self-explanatory. We have minimized the amount of prior knowledge required for the reader by providing the basics of each concept. This reference book is meant to be used day to day and provides many useful tables (used for data interpretation), figures and factoids. The factoids are intended to be short and relevant to the topic discussed that would allow another dimension to the discussions.

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