B

Adults

MONTHS YEARS

Figure 4.1 Age-related patterns of physiological change affecting drug disposition. (A) Changes in metabolic capacity. (B) Changes in body water compartments. (C) Changes in renal function. (Source: From Kearns et al.1 ) With permission from the New England Journal of Medicine.

Adults

MONTHS YEARS

Figure 4.1 Age-related patterns of physiological change affecting drug disposition. (A) Changes in metabolic capacity. (B) Changes in body water compartments. (C) Changes in renal function. (Source: From Kearns et al.1 ) With permission from the New England Journal of Medicine.

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