Changing Pharmaceutical Perspectives

From the earliest of times, humanity has relied on natural sources for its medical needs.7 But this picture began to change in 1805 when the medicinal value of opium was identified with its content of morphine. The isolation of caffeine and quinine in 1819, of codeine in 1832, and of papaverine in 1848 led medicinal and physiological chemists to purify, modify, and synthesize the biologically active components of natural products. Subsequently these substances provided a rich source of new drugs.

At the beginning of the twentieth century, epinephrine was one of the first of these naturally occurring substances to be obtained in pure form, and during the

Gene-targeted therapy

Drug Sources

Genetic engineering i

Gene-targeted therapy

Genetic engineering

Epinephrine Aspirin Penicillins Sulfonamides

Tacrolimus

Epinephrine Aspirin Penicillins Sulfonamides

Tacrolimus

Innovative Drugs

New Therapeutic Cycles

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