When two or more drugs are given that are metabolized by the same enzyme they will compete with each other for that enzyme. If the enzyme is present in sufficient amount or high enough activity, no additional problems from the drug
Trait caused by 4 alleles
Candidate gene strategy
Two candidate genes
Gene association strategy High density SNP map ' ' ' 1 1 ' ' ' ' 1 1 1
Association study All 4 genes found a_A
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