Malditof

sequence analysis

2002 MALDI-TOF analysis for rapid bacterial pathogen identification

MALDI-TOF primer extension analysis in association studies

2003 MALDI-TOF comparative sequence analysis

The yeast two-hybrid (Y2H) system made possible identification of interactions between protein pairs without prior purification

NCBI-BLAST exists in many different forms (see www.ncbi.nlm.nih.gov/ BLAST/producttable. Html)

DNA probe collections immobilized on membranes are interrogated by DNA samples

The potential utility of arrays of immobilized DNA probe sequences for analysis of cDNA target sequences was tested

Microarrays composed of immbolized Arabidopsis cDNAs and expressed sequence tags were used to measure quantitative gene expression of the corresponding genes

The utility of microarrays to pinpoint gene variants in melanoma cancer cell lines is shown

Software that emphasizes objective criteria to measure the accuracy of DNA sequences and assemblies

The high resolution needed for the estimation of mass accuracy is substantially improved by (1) increased delay time between ion generation and ion fragmentation, and (2) more efficient salt removal

Base-specific fragmentation of amplified 16S rRNA gene fragments analyzed by MS offers a tool for rapid identification of bacterial pathogens

Primer extension analysis by MALDI-TOF MS provides reliable estimates of allele frequencies in and between pooled DNAs, and of sources of variability in these estimates

This high-throughput comparative sequence analysis comprises a homogeneous in vitro RNase T1-mediated base-specific cleavage system coupled with MALDI-TOF MS, which enables automated sequence analysis of PCR products up to 1 kb in length to be analyzed

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