1. Silverman PH. Rethinking genetic determinism. Scientist 2004; 18(10):32-33.

2. Baltimore D. Our genome unveiled. Nature 2001; 409(6822):814-816.

3. Waddington CH. Canalization of development and the inheritance of acquired characters. Nature 1942; 150:563-565.

4. Ruden DM, Garfinkel MD, Sollars VE, Lu X. Waddington's widget: Hsp90 and the inheritance of acquired characters. Semin Cell Dev Biol 2003; 14(5):301-310.

5. Barr ML, Bertram EG. A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar staellite during accelerated nucle-oprotein synthesis. Nature 1949; 163(Apr 30):676-677.

6. Ohno S, Kaplan WD, Kinosita R. Formation of the sex chromatin by a single X-chromosome in liver cells of Rattus norvegicus. Exp Cell Res 1959; 18:415-418.

7. Lyon MF. X-chromosome inactivation: A repeat hypothesis. Cytogenet Cell Genet 1998; 80(1-4):133-137.

8. Beutler E, Yeh M, Fairbanks VF. The normal human female as a mosaic of X-chromosome activity: Studies using the gene for C-6-PD-deficiency as a marker. Proc Natl Acad Sci USA 1962; 48:9-16.

9. Crouse H. The controlling element in sex chromosome behavior in Sciara. Genetics 1960; 45:1429-1443.

10. Josse J, Kaiser AD, Kornberg A. Enzymatic synthesis of deoxyribonucleic acid. VIII. Frequencies of nearest neighbor base sequences in deoxyribonucleic acid. J Biol Chem 1961; 236:864-875.

11. Grippo P, Iaccarino M, Parisi E, Scarano E. Methylation of DNA in developing sea urchin embryos. J Mol Biol 1968; 36(2):195-208.

12. Hotchkiss RD. The quantitative separation of purines, pyrimidines, and nucleosides by paper chromatography. J Biol Chem 1948; 175:315-332.

13. Scarano E. The control of gene function in cell differentiation and in embryogenesis. Adv Cytopharmacol 1971; 1:13-24.

14. Salser W. Globin mRNA sequences: Analysis of base pairing and evolutionary implications. CSHL 1977; XLVII:985-1003.

15. Bird AP. DNA methylation and the frequency of CpG in animal DNA. Nucleic Acids Res 1980; 8(7):1499-1504.

16. Bird AP, Taggart MH. Variable patterns of total DNA and rDNA methylation in animals. Nucleic Acids Res 1980; 8(7):1485-1497.

17. Riggs AD. X inactivation, differentiation, and DNA methylation. Cytogenet Cell Genet 1975; 14(1):9-25.

18. Holliday R, Pugh JE. DNA modification mechanisms and gene activity during development. Science 1975; 187(4173):226-232.

19. Jones PA, Taylor SM. Cellular differentiation, cytidine analogs and DNA methylation. Cell 1980; 20(1):85-93.

20. Juttermann R, Li E, Jaenisch R. Toxicity of 5-aza-2'-deoxycytidine to mammalian cells is mediated primarily by covalent trapping of DNA methyltransferase rather than DNA demethylation. Proc Natl Acad Sci USA 1994; 91(25):11797-11801.

21. Gardiner-Garden M, Frommer M. CpG islands in vertebrate genomes. J Mol Biol 1987; 196(2):261-282.

22. Takai D, Jones PA. Comprehensive analysis of CpG islands in human chromosomes 21 and 22. Proc Natl Acad Sci USA 2002; 99(6):3740-3745.

23. Rothnie HM, McCurrach KJ, Glover LA, Hardman N. Retrotransposon-like nature of the Tp1 elements: Implications for the organisation of highly repetitive, hy-permethylated DNA in the genome of Physarum polycephalum. Nucleic Acids Res 1990; 19(2):279-287.

24. Vardimon L, Kressmann A, Cedar H, Maechler M, Doerfler W. Expression of a cloned adenovirus gene is inhibited by in vitro methylation. Proc Natl Acad Sci USA 1982; 79(4):1073-1077.

25. Groudine M, Eisenman R, Weintraub H. Chromatin structure of endogenous ret-roviral genes and activation by an inhibitor of DNA methylation. Nature 1981; 292(5821):311-317.

26. McGrath J, Solter D. Completion of mouse embryogenesis requires both the maternal and paternal genomes. Cell 1984; 37(1):179-183.

27. Spence JE, Perciaccante RG, Greig GM, Willard HF, Ledbetter DH, Hejtmancik JF, et al. Uniparental disomy as a mechanism for human genetic disease. Am J Hum Genet 1988; 42(2):217-226.

28. Monk M. Genomic imprinting. Memories of mother and father. Nature 1987; 328 (6127):203-204.

29. Stoger R, Kubicka P, Liu CG, Kafri T, Razin A, Cedar H, et al. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 1993; 73(1):61-71.

30. Barlow DP. Imprinting: A gamete's point of view. Trends Genet 1994; 10(6):194-199.

31. Brown SW. Heterochromatin. Science 1966; 151(709):417-425.

32. Kimmins S, Sassone-Corsi P. Chromatin remodelling and epigenetic features of germ cells. Nature 2005; 434(7033):583-589.

33. Luger K, Mader AW, Richmond RK, Sargent DF, Richmond TJ. Crystal structure of the nucleosome core particle at 2.8 A resolution. Nature 1997; 389(6648):251-260.

34. Luo RX, Dean DC. Chromatin remodeling and transcriptional regulation. J Natl Cancer Inst 1999; 91(15):1288-1294.

Razin A, Riggs AD. DNA methylation and gene function. Science 1980; 210(4470): 604-610.

Waalwijk C, Flavell RA. MspI, an isoschizomer of hpall which cleaves both un-methylated and methylated hpall sites. Nucleic Acids Res 1978; 5(9):3231-3236. Southern EM. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol 1975; 98:503-517.

Waalwijk C, Flavell RA. DNA methylation at a CCGG sequence in the large intron of the rabbit beta-globin gene: Tissue-specific variations. Nucleic Acids Res 1978; 5(12):4631-4634.

Bestor T, Laudano A., Mattaliano R, Ingram V. Cloning and sequencing of a cDNA encoding DNA methyltransferase of mouse cells. The carboxy-terminal domain of the mammalian enzymes is related to bacterial restriction methyltransferases. J Mol Biol 1988; 203(4):971-983.

Bestor TH. The DNA methyltransferases of mammals. Hum Mol Genet 2000; 9(16):2395-2402.

Wu JC, Santi DV. Kinetic and catalytic mechanism of Hhal methyltransferase. J Biol Chem 1987; 262(10):4778-4786.

Pradhan S, Bacolla A, Wells RD, Roberts RJ. Recombinant human DNA (cytosine-5) methyltransferase. I. Expression, purification, and comparison of de novo and maintenance methylation. J Biol Chem 1999; 274(46):33002-33010. Lei H, Oh SP, Okano M, Juttermann R, Goss KA, Jaenisch R, et al. De novo DNA cytosine methyltransferase activities in mouse embryonic stem cells. Development 1996; 122(10):3195-3205.

Li E, Bestor TH, Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992; 69(6):915-926.

Leonhardt H, Page AW, Weier HU, Bestor TH. A targeting sequence directs DNA methyltransferase to sites of DNA replication in mammalian nuclei. Cell 1992; 71(5):865-873.

Robertson KD, Jones PA. DNA methylation: Past, present and future directions. Carcinogenesis 2000; 21(3):461-467.

Yen RW, Vertino PM, Nelkin BD, Yu JJ, el Deiry W, Cumaraswamy A, et al. Isolation and characterization of the cDNA encoding human DNA methyltransfe-rase. Nucleic Acids Res 1992; 20(9):2287-2291.

Yoder JA, Bestor TH. A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast. Hum Mol Genet 1998; 7(2):279-284.

Van den Wygaert, I, Sprengel J, Kass SU, Luyten WH. Cloning and analysis of a novel human putative DNA methyltransferase. FEBS Lett 1998; 426(2):283-

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook

Post a comment