References

1. Tsien, R.Y. (1998) The green fluorescent protein. Annu Rev Biochem. 67,509-544.

2. Shimomura, O., Johnson, F.H., Saiga, Y. (1962) Extraction, purification and properties of aequorin, a bioluminescent protein from the luminous hydromedusan, Aequorea. J Cell Comp Physiol. 59, 223-239.

3. Griffin, B.A., Adams, S.R., Tsien, R.Y. (1998) Specific covalent labeling of recombinant protein molecules inside live cells. Science. 281, 269-272.

4. Keppler, A., Pick, H., Arrivoli, C., Vogel, H., Johnsson, K. (2004) Labeling of fusion proteins with synthetic fluorophores in live cells . Proc Natl Acad Sci U S A. 101, 9955 - 9959 .

5. George, N., Pick, H., Vogel, H., Johnsson, N., Johnsson, K. (2004). Specific labeling of cell surface proteins with chemically diverse compounds. J Am Chem Soc. 126, 8896 - 8897 .

6. Miyawaki, A., Llopis, J., Heim, R., McCaffery, J.M., Adams, J.A., Ikura, M., Tsien, R.Y. (1997) Fluorescent indicators for Ca2+ based on green fluorescent proteins and calmodulin. Nature. 388 , 882 - 887 .

7. Xu, Y., Piston, D.W., Johnson, C.H. (1999) A bioluminescence resonance energy transfer (BRET) system: Application to interacting circadian clock proteins . Proc Natl Acad Sci U S A. 96,151-156.

8. Giepmans, B.N., Adams, S.R., Ellisman, M.H., Tsien, R.Y. (2006) The fluorescent toolbox for assessing protein location and function. Science. 312, 217-224.

9. Patterson, G.H., Lippincott-Schwartz, J. (2002) A photoactivatable GFP for selective photolabeling of proteins and cells. Science. 297, 1873-1877.

10. Shaner, N.C., Lin, M.Z., McKeown, M.R., Steinbach, P.A., Hazelwood, K.L., Davidson, M.W., Tsien, R.Y. (2008) Improving the photostability of bright monomeric orange and red fluorescent proteins. Nat Methods. 5 , 545 - 551 .

11. Ghosh, I., Hamilton, A.D., Regan, L. (2000) Antiparallel leucine zipper-directed protein reassembly: Application to the green fluorescent protein. J Am Chem Soc. 122 , 5658 - 5659 .

12. Neu-Hynes,T.R., Yost, E., Mervine, S., Berlot, C.H. (2008) Multicolor BiFC analysis of competition among G protein beta and gamma subunit interactions. Methods. 45 , 207 - 213 .

13. Gandia, J., Galino, J., Amaral, O.B., Soriano, A., Lluis, C., Franco, R., Ciruela, F. (2008) Detection of higher-order G protein-coupled receptor oligomers by a combined BRET-BiFC technique. FEBS Lett. 582, 2979-2984.

14. Scherrer, G., Tryoen-Toth, P., Filliol, D., Matifas, A., Laustriat, D., Cao, Y.Q., Basbaum, A.I., Dierich, A., Vonesh, J.L., Gaveriaux-Ruff, C., Kieffer, B.L. (2006) Knockin mice expressing fluorescent delta-opioid receptors uncover G proteincoupled receptor dynamics in vivo. Proc Natl Acad Sci U S A. 103, 9691-9696.

15. Kallal, L., Benovic, J.L. (2000) Using green fluorescent proteins to study G-protein-coupled receptor localization and trafficking. Trends Pharmacol Sci. 21,175-180.

16. Gether, U., Lin, S., Kobilka, B.K. (1995) Fluorescent labeling of purified beta 2 adrenergic receptor. Evidence for ligand-specific conformational changes. J Biol Chem. 270, 28268-28275.

17. Kobilka, B.K., Deupi, X. (2007) Conformational complexity of G-protein-coupled receptors. Trends Pharmacol Sci. 28 , 397 - 406 .

18. Kobilka , B.K. ( 2007 ) G protein coupled receptor structure and activation . Biochim Biophys Acta. 1768,794-807.

19. Harikumar,K.G.,Pinon,D.I.,Wessels,W.S.,Dawson,E.S.,Lybrand,T.P.,Prendergast, F.G., Miller, L.J. (2004) Measurement of intermolecular distances for the natural agonist peptide docked at the cholecystokinin receptor expressed in situ using fluorescence resonance energy transfer. Mol Pharmacol. 65 , 28 - 35 .

20. Harikumar, K.G., Miller, L.J. (2005) Fluorescence resonance energy transfer analysis of the antagonist- and partial agonist- occupied states of the cholecystokinin receptor. J Biol Chem. 280 , 18631 - 18635 .

21. Harikumar, K.G., Lam, P.C., Dong, M., Sexton, P.M., Abagyan, R., Miller, L.J. (2007) Fluorescence resonance energy transfer analysis of secretin docking to its receptor: Mapping distances between residues distributed throughout the ligand pharmaco-phore and distinct receptor residues. J Biol Chem. 282 , 32834 - 32843 .

22. Castro, M., Nikolaev, V.O., Palm, D., Lohse, M.J., Vilardaga, J.P. (2005) Turn-on switch in parathyroid hormone receptor by a two-step PTH binding mechanism. Proc Natl Acad Sci U S A. 102,16084-16089.

23. Shi, L., Javitch, J.A. (2002) The binding site of aminergic G protein-coupled receptors: The transmembrane segments and second extracellular loop. Annu Rev Pharmacol Toxicol. 42 , 437 - 467 .

24. Daly, C.J., McGrath, J.C. (2003) Fluorescent ligands, antibodies, and proteins for the study of receptors. Pharmacol Ther. 100,101-118.

25. Middleton, R.J., Kellam, B. (2005) Fluorophore-tagged GPCR ligands. Curr Opin Chem Biol. 9 , 517 - 525 .

26. Adams, S.R., Campbell, R.E., Gross, L.A., Martin, B.R., Walkup, G.K., Yao, Y., Llopis, J., Tsien, R.Y. (2002) New biarsenical ligands and tetracysteine motifs for protein labeling in vitro and in vivo: Synthesis and biological applications. J Am Chem Soc. 124, 6063-6076.

27. Griffin, B.A., Adams, S.R., Tsien, R.Y. (1998) Specific covalent labeling of recombinant protein molecules inside live cells. Science. 281 , 269 - 272 .

28. Martin, B.R., Giepmans, B.N., Adams, S.R., Tsien, R.Y. (2005) Mammalian cell-based optimization of the biarsenical-binding tetracysteine motif for improved fluorescence and affinity. Nat Biotechnol. 23,1308-1314.

29. Hoffmann, C., Gaietta, G., Bünemann, M., Adams, S.R., Oberdorff-Maass, S., Behr,

B., Vilardaga, J.P.,Tsien, R.Y., Ellisman, M.H., Lohse, M.J. (2005) A FlAsH-based FRET approach to determine G protein-coupled receptor activation in living cells. Nat Methods. 2,171-176.

30. Hein, P., Frank, M., Hoffmann, C., Lohse, M.J., Bünemann, M. (2005) Dynamics of receptor/G protein coupling in living cells. EMBO J. 24, 4106-4114.

31. Hein, P., Rochais, F., Hoffmann, C., Dorsch, S.,Nikolaev,V.O., Engelhardt, S., Berlot,

C.H., Lohse, M.J., Bünemann, M. (2006) Gs activation is time-limiting in initiating receptor-mediated signaling. JBiol Chem. 281, 33345-33351.

32. Rochais, F., Vilardaga, J.P., Nikolaev, V.O., Bünemann, M., Lohse, M.J., Engelhardt, S. (2007) Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol. J Clin Invest. 117,229-235.

33. Nikolaev, V.O. , Hoffmann , C. , B ü nemann , M. , Lohse, M.J. , Vilardaga , J.P. ( 2006 ) Molecular basis of partial agonism at the neurotransmitter {alpha}2A-adrenergic receptor and Gi-protein heterotrimer. J Biol Chem. 281, 24506-24511.

34. Lohse, M.J., Nikolaev, V.O., Hein, P., Hoffmann, C., Vilardaga, J.P., Bünemann, M. (2008) Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends Pharmacol Sci. 29,159-165.

35. Spagnuolo, C.C., Vermeij, R.J., Jares-Erijman, E.A. (2006) Improved photostable FRET-competent biarsenical-tetracysteine probes based on fluorinated fluoresceins. J Am Chem Soc. 128,12040-12041.

36. Keppler, A., Arrivoli, C., Sironi, L., Ellenberg, J. (2006) Fluorophores for live cell imaging of AGT fusion proteins across the visible spectrum. Biotechniques. 41, 167-170.

37. Böhme, I., Morl, K., Bamming, D., Meyer, C., Beck-Sickinger, A.G. (2007) Tracking of human Y receptors in living cells—A fluorescence approach. Peptides. 28, 226 - 234 .

38. Meyer, B.H., Martinez, K.L., Segura, J.M., Pascoal, P., Hovius, R., George, N., Johnsson, K., Vogel, H. (2006) Covalent labeling of cell-surface proteins for in-vivo FRET studies. FEBS Lett. 580,1654-1658.

39. Meyer, B.H., Segura, J.M., Martinez, K.L., Hovius, R., George, N., Johnsson, K., Vogel, H. (2006) FRET imaging reveals that functional neurokinin-1 receptors are monomeric and reside in membrane microdomains of live cells. Proc Natl Acad Sci U S A. 103,2138-2143.

40. Maurel , D. , Comps - Agrar, L. , Brock , C. , Rives, M.L. , Bourrier, E. , Ayoub, M.A. , Bazin,H.,Tinel,N.,Durroux,T.,Prezeau,L.,Trinquet,E.,Pin, J.P. (2008) Cell-surface protein-protein interaction analysis with time-resolved FRET and snap-tag technologies: Application to GPCR oligomerization. Nat Methods. 5,561-567.

41. Gautier, A., Juillerat, A., Heinis, C., Correa Jr., I.R., Kindermann, M., Beaufils, F., Johnsson . K. (2008). An engineered protein tag for multiprotein labeling in living cells. Chem Biol. 15 , 128 - 136 .

42. Wang, B., Bisello,A.,Yang,Y., Romero, G.G., Friedman, P.A. (2007) NHERF1 regulates parathyroid hormone receptor membrane retention without affecting recycling. J Biol Chem. 282, 36214-36222.

43. Bockaert, J., Fagni, L., Dumuis, A., Marin, P. (2004) GPCR interacting proteins (GIP) Pharmacol Ther. 103, 201-221.

44. Drake, M.T., Shenoy, S.K., Lefkowitz, R.J. (2007) Trafficking of G protein-coupled receptors. Circ Res. 99, 570-582.

45. Willig, K.I., Rizzoli, S.O., Westphal, V., Jahn, R., Hell, S.W. (2006) STED microscopy reveals that synaptotagmin remains clustered after synaptic vesicle exocytosis. Nature. 440, 935-939.

46. Puthenveedu, M.A., Yudowski, G.A., von Zastrow, M. (2007) Endocytosis of neurotransmitter receptors: Location matters. Cell. 130, 988-989.

47. Eidne, K.A., Kroeger, K.M., Hanyaloglu, A.C. (2002) Applications of novel resonance energy transfer techniques to study dynamic hormone receptor interactions in living cells. Trends Endocrinol Metabol. 13,415-421.

48. Ramsay, D. , Kellett , E. , McVey, M. , Rees, S. , Milligan , G. ( 2002 ) Homo and hetero -oligomeric interactions between G protein-coupled receptors in living cells monitored by two variants of bioluminescence resonance energy transfer (BRET): Hetero-oligomers between receptor subtypes form more efficiently than between less closely related sequences. Biochem J. 365, 429-440.

49. Milligan, G. (2004) Applications of bioluminescence- and fluorescence resonance energy transfer to drug discovery at G protein-coupled receptors. Eur J Pharm Sci. 21, 397-405.

50. Kremers, G.J., Goedhart, J., van Munster, E.B., Gadella Jr.,T.W. (2006) Cyan and yellow super fluorescent proteins with improved brightness, protein folding, and FRET Förster radius. Biochem. 45, 6570-6580.

51. Bazin, H., Trinquet, E., Mathis, G. (2002) Time resolved amplification of cryptate emission: A versatile technology to trace biomolecular interactions. J Biotechnol. 82 , 233 - 250 .

52. van Rijn, R.M., Chazot, P.L., Shenton, F.C., Sansuk, K., Bakker, R.A., Leurs, R. (2006) Oligomerization of recombinant and endogenously expressed human hista-mine H(4) receptors. Mol Pharmacol. 70, 604-615.

53. Roy, R. , Hohng, S. , Ha , T. ( 2008 ) A practical guide to single - molecule FRET. Nat Methods. 5, 507-516.

54. van Munster, E.B., Gadella, T.W. (2005) Fluorescence lifetime imaging microscopy (FLIM). Adv Biochem Eng Biotechnol. 95,143-175.

55. Janetopoulos, C., Jin,T., Devreotes, P. (2001) Receptor-mediated activation of het-erotrimeric G-proteins in living cells. Science. 291, 2408-2411.

56. Gilman, A.G. (1987) G proteins: Transducers of receptor-generated signals. Annu Rev Biochem. 56, 615-649.

57. Bünemann, M., Frank, M., Lohse, M.J. (2003) Gi protein activation in intact cells involves subunit rearrangement rather than dissociation. Proc Natl Acad Sci U S A. 100,16077-16082.

58. Levitzki , A. , Klein , S. , Reuveni , H. ( 2002 ) G - protein subunit dissociation is not an integral part of G-protein action signal transduction by a nondissociable heterotri-meric yeast G protein. Chembiochem. 3, 815-818.

59. Robishaw, J.D., Berlot, C.H. (2004) Translating G protein subunit diversity into functional specificity. Curr Opin Cell Biol. 16 , 206 - 209 .

60. Gales, C., Van Durm, J.J., Schaak, S., Pontier, S., Percherancier, Y., Audet, M., Paris, H., Bouvier, M. (2006) Probing the activation-promoted structural rearrangements in preassembled receptor-G protein complexes. Nat Struct Mol Biol. 13, 778-786.

Digby,G.J.,Lober,R.M.,Sethi,P.R.,Lambert,N.A. (2006) Some G protein heterotri-mers physically dissociate in living cells. Proc Natl Acad Sci U S A. 103,17789-17794. Frank, M., Thumer, L., Lohse, M.J., Bunemann, M. (2005) G protein activation without subunit dissociation depends on a G{alpha}(i)-specific region. J Biol Chem. 280, 24584-24590.

Nobles, M., Benians, A., Tinker, A. (2005) Heterotrimeric G proteins precouple with G protein-coupled receptors in living cells. Proc Natl Acad Sci U S A. 102 , 18706-18711.

Galés, C., Rebois, R.V., Hogue, M., Trieu, P., Breit, A., Hébert, T.E., Bouvier, M. (2005) Real-time monitoring of receptor and G-protein interactions in living cells. Nat Methods. 2 , 177 - 184 .

Qin, K., Sethi, P.R., Lambert, N.A. (2008) Abundance and stability of complexes containing inactive G protein- coupled receptors and G proteins. FASEB J. 22 , 2920-2927.

Palczewski, K., Saari, J.C. (1997) Activation and inactivation steps in the visual transduction pathway. Curr Opin Neurobiol. 7, 500-504.

Luttrell, L.M., Lefkowitz, R.J. (2002) The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci. 115,455-465. Bunemann, M., Hosey, M.M. (1999) G-protein coupled receptor kinases as modulators of G-protein signalling. J Physiol. 517, 5-23.

Barak, L.S., Ferguson, S.S., Zhang, J., Caron, M.G. (1997) A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation. J Biol Chem. 272, 27497-27500.

Pfleger, K.D., Dalrymple, M.B., Dromey, J.R., Eidne, K.A. (2007) Monitoring interactions between G-protein-coupled receptors and beta-arrestins. Biochem Soc Trans. 35 , 764 - 766 .

Krasel, C., Bunemann, M., Lorenz, K., Lohse, M.J. (2005) p-Arrestin binding to the p2-adrenergic receptor requires both receptor phosphorylation and receptor activation. J Biol Chem. 280, 9528-9535.

Violin, J.D., Ren, X.R., Lefkowitz, R.J. (2006) G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer. J Biol Chem. 281, 20577-20588. Vilardaga,J.P.,Bunemann,M.,Krasel, C.,Castro,M.,Lohse,M. J. (2003) Measurement of millisecond activation switch of G protein-coupled receptors in living cells. Nat Biotech. 7 , 807 - 812 .

Scheerer, P., Park, J.H., Hildebrand, P.W., Kim, Y. J., Krauss, N., Choe, H.W., Hofmann, K.P., Ernst, O.P. (2008) Crystal structure of opsin in its G-protein-interacting conformation . Nature. 455 , 497 - 502 .

Park, J.H., Scheerer, P., Hofmann, K.P., Choe, H.W., Ernst, O.P. (2008) Crystal structure of the ligand-free G-protein-coupled receptor opsin. Nature. 454,183-187. Hille, B. (2001) Ionic Channels ofExcitable Membranes, 3rd ed. Sunderland, MA: Sinauer.

Pioszak, A.A., Xu, H.E. (2008) Molecular recognition of parathyroid hormone by its G protein-coupled receptor. Proc Natl Acad Sci U S A. 105, 5034-5039. Vilardaga, J.P., Steinmeyer, R., Harms, G.S., Lohse, M.J. (2005) Molecular basis of inverse agonism in a G protein-coupled receptor. Nat Chem Biol. 1, 25-28.

0 0

Post a comment