The Effects of Maturational Changes on Drug Disposition

Traditionally, drug dosing in infants and children has been based on age or weight ratio reduction of the adult dose. Data compiled in the past 40 years on maturational changes in

Table 2 Mostly Accepted Classifications for Defining Elder Subpopulations

Criterion

Method

Cutoff

Time

Chronological

65 yr (65-74 yr: young old, 75-84 yr:

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