Info

monkeys

aThe assay method can greatly influence measured affinity values; therefore, affinity comparisons should only be made within a given study unless identical assay methods are used.

bCompared with WT at pH 6.0. cCompared with WT at pH 7.4. Percentage bound to FcRn at pH 7.4.

Abbreviations-. Kd, dissociation constant; PK, pharmacokinetics; CD, cluster of differentiation; WT, wild type; FcRn, neonatal fragment crystallizable receptor.

aThe assay method can greatly influence measured affinity values; therefore, affinity comparisons should only be made within a given study unless identical assay methods are used.

bCompared with WT at pH 6.0. cCompared with WT at pH 7.4. Percentage bound to FcRn at pH 7.4.

Abbreviations-. Kd, dissociation constant; PK, pharmacokinetics; CD, cluster of differentiation; WT, wild type; FcRn, neonatal fragment crystallizable receptor.

0 0

Post a comment