Vasoactive substances

Substances released from many cells and tissues in the body, including the endothelium lining blood vessels, endocrine glands, and myocytes in the heart, may affect vascular smooth muscle tone. These substances may stimulate this muscle to cause vasoconstriction or inhibit it to cause vasodilation. As expected, vasoconstriction will increase TPR (and therefore MAP) and vasodilation will decrease TPR (and therefore MAP). Vasoconstrictors. Many substances produced in the human body cause...

Essentials For Human Physiology

AHFS Drug Information 2000, American Society of Health-System Pharmacists, Bethesda, MD, 2000. 2. Bell, D.R., Core Concepts in Physiology, Lippincott-Raven Publishers, Philadelphia, 1998. 3. Costanzo, L., Physiology, W.B. Saunders, Philadelphia, 1998. 4. Guyton, A.C. and Hall, J.E., Textbook of Medical Physiology, 10th ed., W.B. Saunders, Philadelphia, 2000. 5. Hunt, M.L., Jr., Training Manual for Intravenous Admixture Personnel, 5th ed., Baxter Healthcare Corp., 1995. 6. Lombard, J.H. and...