Historical Aspects

The first description of liquid-liquid partition chromatography dates back to the work of Martin and Synge who worked on the extraction of natural products using counter-current extraction in 1941 [11]. While the early forms of liquid-liquid partition chromatography did not appear very promising for practical purposes, Martin and Synge received the highest awards for their pioneering concept. More than 20 years later, the emergence and extensive commercialization of high-performance liquid chromatography (HPLC) have become so popular that HPLC techniques are a must for every modern analytical chemical laboratory, while liquid-liquid partition chromatography remains relatively obscure.

0 0

Post a comment