AMSTERDAM • BOSTON • HEIDELBERG • LONDON • NEW YORK • OXFORD PARIS • SAN DIEGO • SAN FRANCISCO • SINGAPORE • SYDNEY • TOKYO
Academic Press is an imprint of Elsevier 32 Jamestown Road, London NW1 7BY, UK 30 Corporate Drive, Suite 400, Burlington, MA 01803, USA 525 B Street, Suite 1900, San Diego, CA 92101-4495, USA
First edition 2010
Copyright © 2010 Elsevier Inc. All rights reserved
No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means electronic, mechanical, photocopying, recording or otherwise without the prior written permission of the publisher. Permissions may be sought directly from Elsevier's Science & Technology Rights Department in Oxford, UK: phone (+ 44) (0) 1865 843830; fax (+44) (0) 1865 853333; email: [email protected]. Alternatively, visit the Science and Technology Books website at www.elsevierdirect.com/rights for further information
Cover Image: Two views of the X-ray crystallographic structure of the complete Thermus thermophilus 70S ribosome containing bound messenger RNA and transfer RNAs at 5.5-A resolution (from Yusupov, M. M., Yusupova, G. Z., Baucom, A., Lieberman, K., Earnest, T. N., Cate, J. H., and Noller, H. F. (2001) Science 292, 883-96 with permission). Perhaps Natures's most complicated molecular machine, the ribosome consists of RNA and proteins that work together to accomplish the multiple structural, catalytic, and force-generating steps required for the high-fidelity synthesis and elongation of polypeptides. Although the centerpiece of the 2009 Nobel Prizes in Chemistry, the ribosome remains a major challenge for enzyme scientists and kineticists seeking to unlock its many secrets.
No responsibility is assumed by the publisher for any injury and/or damage to persons or property as a matter of products liability, negligence or otherwise, or from any use or operation of any methods, products, instructions or ideas contained in the material herein. Because of rapid advances in the medical sciences, in particular, independent verification of diagnoses and drug dosages should be made
British Library Cataloguing-in-Publication Data
A catalogue record for this book is available from the British Library
Library of Congress Cataloging-in-Publication Data
A catalog record for this book is available from the Library of Congress
For information on all Academic Press publications visit our website at elsevierdirect.com
Typeset by TNQ Books and Journals Pvt Ltd. www.tnq.co.in
Printed and bound in China
Was this article helpful?
Thousands Have Used Chemicals To Improve Their Medical Condition. This Book Is one Of The Most Valuable Resources In The World When It Comes To Chemicals. Not All Chemicals Are Harmful For Your Body – Find Out Those That Helps To Maintain Your Health.