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Notice that the (1 + [Q]/Kiq) only affects the A term in Eqn. 8.32, indicating that, in a Ping-Pong Bi Bi kinetic mechanism, the presence of product Q should give rise to a competitive inhibition pattern in a 1/v versus 1/[A] plot and an uncompetitive inhibition pattern in a 1/v versus 1/[B] plot (see Fig. 8.25).

The initial-velocity equation for an enzyme operating by the above kinetic scheme is as follows:

Ki ipJ

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