Selection Of Plants

Judicious selection of plants for further evaluation and discovery of new chemopreventive agents is a challenge. The process of selecting and evaluating plants is based on available literature, epidemiological evidence, and traditional medicinal use by people in the region where the plant is available. In addition, wherever possible, priority is given to edible plants. Along these lines, we also utilize the database of plants maintained at the University of Illinois. This valuable resource, Natural Product Alert (NAPRALERT), constitutes a collection of more than 150,000 scientific articles. Thus far, more than 3000 plants have been collected. The various plant parts, such as leaves, roots, stems, or fruit, are extracted with ethyl acetate and evaluated for potential chemopreventive properties using several mechanistically based bioassays.2324

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