Biological Activities and Potential Health Benefits of Fucoxanthin Derived from Marine Brown Algae

Se-Kwon Kim*'t'1 and Ratih Pangestuti*

Contents I. Introduction 112

II. Profiles and Bioavailability of Fucoxanthin 113

III. Biological Activities of Fucoxanthin 115

A. Antioxidant activity 115

B. Anticancer activity 117

C. Anti-inflammatory activity 118

D. Antiobesity activity 119

E. Neuroprotective effect 120

F. Antiangiogenic activity 121

G. Skin protective effect 122

H. Other biological activities 122

IV. Conclusions and Future Perspectives 123 References 123

Abstract The importance of marine algae as sources of functional ingredients has been well recognized due to their valuable health beneficial effects. Therefore, isolation and investigation of novel bioactive ingredients with biological activities from marine algae have attracted great attention. Among functional ingredients identified from marine algae, fucoxanthin has received particular interest.

* Marine Biochemistry Laboratory, Department of Chemistry, Pukyong National University, Busan, Republic of Korea

{ Marine Bioprocess Research Center, Pukyong National University, Busan, Republic of Korea 1 Corresponding author: Se-Kwon Kim, E-mail address: [email protected]

Advances in Food and Nutrition Research, Volume 64 © 2011 Elsevier Inc.

ISSN 1043-4526, DOI: 10.1016/B978-0-12-387669-0.00009-0 All rights reserved.

Fucoxanthin has been attributed with extraordinary potential for protecting the organism against a wide range of diseases and has considerable potential and promising applications in human health. Fucoxanthin has been reported to exhibit various beneficial biological activities such as antioxidant, anticancer, anti-inflammatory, antiobesity, and neuroprotective activities. In this chapter, the currently available scientific literatures regarding the most significant activities of fucoxanthin are summarized.

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