Antidiabetic activity

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels. Diabetes without proper treatments can cause many complications. Acute complications include hypoglycemia, diabetic ketoacidosis, or nonketotic hyperosmolar coma. Serious long-term complications include cardiovascular disease, chronic renal failure, and retinal damage. Hence, antidiabetic agents are urgently required. It has been reported that fucosterol from P. siliquosa have antidiabetic activity. Fucos-terol at a dose of 100 and 300 mg/kg reduced hyperglycemic effect by 25-33% in epinephrine-induced diabetes mouse model. Moreover, fucosterol at a dose of 100 and 300 mg/kg was shown to decrease the glycogen degradation of mouse liver by 23-29%. Hence, it was suggested that fucosterol from marine alga P. siliquosa has potential in development of antidiabetic agent (Lee et al., 2004).

Diabetes Sustenance

Diabetes Sustenance

Get All The Support And Guidance You Need To Be A Success At Dealing With Diabetes The Healthy Way. This Book Is One Of The Most Valuable Resources In The World When It Comes To Learning How Nutritional Supplements Can Control Sugar Levels.

Get My Free Ebook


Post a comment