Eye infection

A recent small case series determination that with a trained eye, biofilm can be visualized in chronic wounds and that its appearance is quite different from that of slough. Because of the differing biochemical compositions of biofilm and slough, different management strategies are required for the removal and control of these substances. Pulsed larvae and enzymatic (proteolytic) debriding agents were efficacious in removing slough but were ineffective against biofilm. Physical debridement (sharp or use of a sterile gauze pad) was more effective than other modalities in removing biofilm, and the daily application of a nontoxic antiseptic solution prevented biofilm redevelopment (Hurlow and Bowler, 2009).

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