Medicinal Effects of Phlorotannins from Marine Brown Algae

Contents I. Introduction 98

II. Phlorotannins 98

III. Medicinal Effects of Phlorotannins 99

A. Antioxidant effects 99

B. Anticancer effects 104

C. Antiallergic effects 105

D. Anti-inflammatory effects 106

E. Antidiabetic effects 106

IV. Conclusions 107 References 107

Abstract Brown seaweeds are popular and abundant food in East Asia and also well known for their medicinal effects due to presence of active phenolic constituents. Phlorotannins, the major phenolic group of brown algae, have extensively investigated for their vast array of bioactivities such as antioxidant, anti-inflammatory, anticancer, and antidiabetic. They possess promising activity in both in vitro and in vivo systems showing promising potential to further develop as therapeutic agents. In this chapter, attempts have taken to examine and categorize the reports available on active phlorotannins which have shown strong bioactivities.

* Marine Biochemistry Laboratory, Department of Chemistry, Pukyong National University, Busan, Republic of Korea

{ Marine Bioprocess Research Center, Pukyong National University, Busan, Republic of Korea 1 Corresponding author: Se-Kwon Kim, E-mail address: [email protected]

Advances in Food and Nutrition Research, Volume 64 © 2011 Elsevier Inc.

ISSN 1043-4526, DOI: 10.1016/B978-0-12-387669-0.00008-9 All rights reserved.

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