Aisa, Y., Miyakawa, Y., Nakazato, T., Shibata, H., Saito, K., Ikeda, Y., and Kizaki, M. (2004). Fucoidan induces apoptosis of human HS-Sultan cells accompanied by activation of caspase-3 and down-regulation of ERK pathways. Am. J. Hematol. 78, 7-14.

Alban, S., Schauerte, A., and Franz, G. (2002). Anticoagulant sulfated polysaccharides: Part I. Synthesis and structure-activity relationships of new pullulan sulfates. Carbohydr. Polym. 47, 267-276.

Albuquerque, I. R. L., Queiroz, K. C. S., Alves, L. G., Santos, E. A., Leite, E. L., and Rocha, H. A. O. (2004). Hetarofucans from Dictyota menstrualis have anticoagulant activity. Braz. J. Med. Biol. Res. 37,167-171.

Alekseyenko, T. V., Zhanayeva, S. Y., Venediktova, A. A., Zvyagintseva, T. N., Kuznetsova, T. A., Besednova, N. N., and Korolenko, T. A. (2007). Antitumor and antimetastatic activity of fucoidan, a sulfated polysaccharide isolated from the Okhotsk sea Fucus evanescens brown alga. Bull. Exp. Biol. Med. 143, 730-732.

Amarowicz, R., Pegg, R. B., Rahimi-Moghaddam, P., Barl, B., and Weil, J. A. (2004). Free-radical scavenging capacity and antioxidant activity of selected plant species from the Canadian prairies. Food Chem. 84, 551-562.

Athukorala, Y., Jung, W. K., Vasanthan, T., and Jeon, Y. J. (2006). An anticoagulative polysaccharide from an enzymatic hydrolysate of Ecklonia cava. Carbohydr. Polym. 66, 184-191.

Athukorala, Y., Lee, K. W., Kim, S. K., and Jeon, Y. J. (2007). Anticoagulant activity of marine green and brown algae collected from Jeju Island in Korea. Bioresour. Technol. 98, 1711-1716.

Athukorala, Y., Ahn, G. N., Jee, Y. H., Kim, G. Y., Kim, S. H., Ha, J. H., Kan, J. S., Lee, K. W., and Jeon, Y. J. (2009). Antiproliferative activity of sulfated polysaccharide isolated from an enzymatic digest of Ecklonia cava on the U-937 cell line. J. Appl. Phycol. 21, 307-314.

Boisson-Vidal, C., Haroun, F., Ellouali, M., Blondin, C., Fischer, A. M., de Agostini, A., and Josefonvicz, J. (1995). Biological activities of polysaccharides from marine algae. Drugs Future 20, 1237-1249.

Chen, W. S., Lazar, C. S., Poenie, M., Tsien, R. Y., Gill, G. N., and Rosenfeld, M. G. (1987). Requirement for intrinsic protein tyrosine kinase in the immediate and late actions of the EGF receptor. Nature 328, 820-823.

Chevolot, L., Foucault, A., and Chauber, F. (1999). Further data on the structure of brown seaweed fucans: Relationships with anticoagulant activity. Carbohydr. Res. 319,154-165.

Chirinos, R., Rogetz, H., Campos, D., Pedreschi, R., and Larondelle, Y. (2007). Optimization of extraction conditions of antioxidant phenolic compounds from mashua (Tropaeolum tuberosum Ruiz & Pavon) tubers. Sep. Purif. Technol. 55, 217-225.

Choi, C. W., Kim, S. C., Hwang, S. S., Choi, B. K., Ahn, H. J., Lee, M. Y., Park, S. H., and Kim, S. K. (2002). Antioxidant activity and free radical scavenging capacity between Korean medicinal plants and flavonoids by assay-guided comparison. Plant Sci. 163, 1161-1168.

Choi, E. M., Kim, A. J., Kim, Y., and Hwang, J. K. (2005). Immunomodulating activity of arabinogalactan and fucoidan in vitro. J. Med. Food 8, 446-453.

Costa, L. S., Fidelis, G. P., Cordeiro, S. L., Oliveira, R. M., Sabry, D. A., Camara, R. B., Nobre, L. T., Costa, M. S., Almeida-Lima, J., Farias, E. H., Leite, E. L., and Rocha, H. A. (2010). Biological activities of sulfated polysaccharides from tropical seaweeds. Biomed. Pharmacother. 64, 21-28.

Davis, T. A., Volesky, B., and Mucci, A. (2003). A review of the biochemistry of heavy metal biosorption by brown algae. Water Res. 37, 4311-4330.

De Zoisa, M., Nikapitiya, C., Jeon, Y. J., Jee, Y., and Lee, J. (2008). Anticoagulant activity of sulfated polysaccharide isolated from brown seaweed Sargassum fulvellum. J. Appl. Phycol. 20, 67-74.

Desai, U. R. (2004). New antithrombin-based anticoagulants. Med. Res. Rev. 24,151-181.

Dietrich, C. P., Farias, G. G. M., Abreu, L. R. D., Leite, E. L., Silva, L. F., and Nader, H. B. (1995). A new approach for characterization of polysaccharides from algae: Presence of four main acidic polysaccharides in three species of the class Phaeophyceae. Plant Sci. 108, 143-153.

Do, H., Kang, N. S., Pyo, S., Billiar, T. R., and Sohn, E. H. (2010). Differential regulation by fucoidan of IFN-g-induced NO production in glial cells and macrophages. Journal of Cell Biochemistry 111, 1337-1345.

Dobashi, K., Nishino, T., and Fujihara, M. (1989). Isolation and preliminary characterization of fucose-containing sulfated polysaccharides with blood-anticoagulant activity from seaweed Hizikiafusiforme. Carbohydr. Res. 194, 315-320.

Eldeen, A. M. G., Ahmed, E. F., and Zeid, M. A. A. (2009). In vitro cancer chemopreventive properties of polysaccharide extract from the brown alga, Sagassum latifolium. Food Chem. Toxicol. 47, 1378-1384.

Grauffel, V., Kloareg, B., Mabeau, S., Durand, P., and Josefonficz, J. (1989). New natural polysaccharides with potent antithrombotic activity: Fucans from brown algae. Biomaterials 10, 363-369.

Hayashi, K., Nakano, T., Hashimoto, M., Kanekiyo, K., and Hayashi, T. (2008). Defensive effects of a fucoidan from brown alga Undaria pinnatifida against herpes simplex virus infection. Int. Immunopharmacol. 8, 109-116.

Hemmingson, J. A., Falshaw, R., Furneaux, R. H., and Thompson, K. (2006). Structure and antiviral activity of the galactofucan sulfates extracted from Undaria pinnatifida (Phaeo-phyta). J. Appl. Phycol. 18, 185-193.

Huynh, R., Chaubet, F., and Jozefonvicz, J. (2001). Anticoagulant properties of dextran-methylcarboxylate benzylamide sulfate (DMCBSu); a new generation of bioactive func-tionalized dextran. Carbohydr. Res. 332, 75-83.

Itoh, H., Noda, H., Amano, H., and Ito, H. (1995). Immunological analysis of lung metastasis by fucoidan (GIV-A) prepared from brown seaweed Sargassum thunbergii. Anticancer Res. 15, 1937-1947.

Jiang, Z., Okimura, T., Yokose, T., Yamasaki, Y., Yamaguchi, K., and Oda, T. (2010). Effect of sulfated, ascophyllan, from the brown alga Ascophyllum nodosum on various cell lines: A comparative study on ascophyllan and fucoidan. J. Biosci. Bioeng. 110, 113-117.

Jintang, S., Alei, F., Yun, Z., Shanzhen, S., Weixu, H., Meixiang, Y., fengcai, W., and Xun, Q. (2010). Fucoidan increases TNF-a-induced MMP-9 secreation monocytic cell line U937. Inflammation Res. 59, 271-276.

Jung, W. K., Athukorala, Y., Lee, Y. J., Cha, S. H., Lee, C. H., Vasanthan, T., Choi, K. S., Yoo, S. H., Kim, S. K., and Jeon, Y. J. (2007). Sulfated polysaccharide purified from Ecklonia cava accelerates antithrombin III-mediated plasma proteinase inhibition. J. Appl. Phycol. 19, 425-430.

Kang, S. M., Kim, K. N., Lee, S. H., Ahn, G., Cha, S. H., Kim, A. D., Yang, X. D., Kang, M. C., and Jeon, Y. J. (2011). Anti-inflammatory activity of polysaccharide purified from AMG-assistant extract of Ecklonia cava in LPS-stimulated RAW264.7 macrophages. Carbohydr. Polym 85, 80-85.

Kazlowska, K., Hsu, T., Hou, C. C., Yang, W. C., and Tsai, G. J. (2010). Antiinflammatory properties of phenolic compounds and crude extract from Porphyra dentata. J. Ethanophar-macol. 128, 123-130.

Khotimchenko, Y. S. (2010). Antitumor properties of nonstarch polysaccharides: Fucoidans and chitosans. Russ. J. Mar. Biol. 36, 321-330.

Kim, T. H. and Bae, J. S. (2010). Ecklonia cava extracts inhibit liposaccharide induced inflammatory responses in human endothelial cells. Food Chem. Toxicol. 48, 1682-1687.

Kim, M. H. and Joo, H. G. (2008). Immunomodulatory effects of fucoidan on bone marrow-derived dendritic cells. Immunol. Lett. 115,138-143.

Kim, K. J., Lee, O. H., and Lee, B. Y. (2010a). Fucoidan, a sulfated polysaccharide, inhibits adipogenesis through the mitogen-activated protein kinase pathway in 3T3-L1 preadi-pocytes. Life Sci. 86, 791-797.

Kim, K. J., Lee, O. H., Lee, H. H., and Lee, B. Y. (2010b). A 4-week repeated oral dose toxicity study of fucoidan from Sporophyll of Undaria pinnatifida in Sprague-Dawley rats. Toxicology 267, 154-158.

Kong, C. S., Kim, J. A., Yoon, N. Y., and Kim, S. K. (2009). Induction of apoptosis by phloroglucinol derivative from Ecklonia cava in MCF-t human breast cancer cells. Food Chem. Toxicol. 47, 1653-1658.

Kuznetsova, T. A., Besednova, N. N., Mamaev, A. N., Momot, A. P., Shevchenko, N. M., and Zvyagintseva, T. N. (2003). Anticoagulant activity of fucoidan from brown algae Fucus evanescens of the Okhotsk sea. Bull. Exp. Biol. Med. 136, 471-473.

Lahaye, M. (1991). Marine algae as sources of fibres: Determination of soluble and insoluble dietary fibre contents in some "sea vegetables''. J. Sci. Food Agric. 54, 587-594.

Lee, N. Y., Ermakova, S. P., Zvyagintseva, T. N., Kang, K. W., Dong, Z., and Choi, S. (2008a). Inhibitory effects of fucoidan on activation of epidermal growth factor receptor and cell transformation in JB6 C141 cells. Food Chem. Toxicol. 46,1793-1800.

Lee, S. H., Athukorala, Y., Lee, J. S., and Jeon, Y. J. (2008b). Simple separation of anticoagulant sulfated galactan from red algae. J. Appl. Phycol. 20,1053-1059.

Li, B., Lu, F., Wei, X., and Zhao, R. (2008). Fucoidan: Structure and bioactivity. Molecules 13, 1671-1695.

Li, C., Gao, Y., Xing, Y., Zhu, H., Shen, J., and Tian, J. (2011). Fucoidan, a sulfated polysaccharide from brown algae, against myocardial ischemia-reperfusion injury in rats via regulating the inflammation response. Food Chem. Toxicol. 49, 2090-2095.

Logeart, D., Prigeant-Richard, S., Jozefonvicz, J., and Letourneur, D. (1997). Fucan, a sulfated polysaccharide extracted from brown seaweeds, inhibits vascular SMC proliferation: Part I.

Comparison with heparin for the antiproliferative activity, binding and internalization. Eur. J. Cell Biol. 74, 385-390.

Mandai, P., Mateu, C. G., Chattopadhyay, K., Pujol, C. A., Damonte, E. B., and Ray, B. (2007). Structural features and antiviral activity of sulphated fucans from the brown seaweed Cystoseira indica. Antivir. Chem. Chemother. 18, 153-162.

Maruyama, H., Tamauchi, H., Hashimoto, M., and Nakano, T. (2003). Antitumor activity and immune response of Mekabu fucoidan extracted from Sporophyll of Undaria pinnatifida. In Vivo 17, 245-249.

Maruyama, H., Tamauchi, H., Iizuka, M., and Nakano, T. (2006). The role of NK cells in antitumor activity of dietary fucoidan from Undaria pinnatifida sporophylls (Mekabu). Planta Med. 72,1415-1417.

Matou, S., Helley, D., Chabut, D., Bros, A., and Fischer, A. M. (2002). Effect of fucoidan on fibroblast growth factor-2-induced angiogenesis in vitro. Thromb. Res. 106, 213-221.

Matsubara, K., Matsuura, Y., Hori, K., and Miyazawa, K. (2000). An anticoagulant proteoglycan from the marine green alga, Codium pugniformis. J. Appl. Phycol. 12, 9-14.

Matsuhiro, B., Zuniga, E., Jashes, M., and Guacucano, M. (1996). Sulfated polysaccharides from Durvillaea antarctica. Hydrobiologia 321, 77-81.

Mestechkina, N. M. and Shcherbukhin, V. D. (2010). Sulfated polysaccharides and their anticoagulant activity: A review. Appl. Biochem. Microbiol. 46, 267-273.

Nishino, T. and Nagumo, T. (1992). Anticoagulant and antithrombin activities of oversulfated fucans. Carbohydr. Res. 229, 355-362.

Pereira, M. S., Silva, A. C. E. S. V., Valente, A. P., and Mourao, P. A. S. (2002). A 2-sulfated, 3-linked a-L-galactan is an anticoagulant polysaccharide. Carbohydr. Res. 337, 2231-2238.

Qui, X., Amarasekara, A., and Doctor, V. (2006). Effect of oversulfation on the chemical and biological properties of fucoidan. Carbohydr. Polym. 63, 224-228.

Reddy, P. and Urban, S. (2009). Meroditerpenoids from the southern Australian marine brown alga Sargassum fallax. Phytochemistry 70, 250-255.

Senni, K., Gueniche, F., Bertaud, A. F., Tchen, S. I., Fioretti, F., Jouault, S. C., Durand, P., Guezennec, J., Godeau, G., and Letourneur, D. (2006). Fucoidan a sulfated polysaccharide from brown algae is a potent modulator of connective tissue proteolysis. Arch. Biochem. Biophys. 445, 56-64.

Shibata, T., Ishimaru, K., Kawaguchi, S., Yoshikawa, H., and Hama, Y. (2008). Antioxidant activities of phlorotannins isolated from Japanese Laminariacea. J. Appl. Phycol. 20, 705-711.

Silva, T. M. A., Alves, L. G., Queiroz, K. C. S., Santos, M. G. L., Marques, C. T., Chavante, S. F., Rocha, H. A. O., and Leite, E. L. (2005). Partial characterization and anticoagulant activity of a heterofucan from the brown seaweed Padina gymnospora. Braz. J. Med. Biol. Res. 38, 523-533.

Soeda, S., Sakaguchi, S., Shimeno, H., and Nagamatsu, A. (1992). Fibrinolytic and anticoagulant activities of highly sulfated fucoidan. Biochem. Pharmacol. 43,1853-1858.

Synytsya, A., Kim, W. J., Kim, S. M., Pohl, R., Synytsya, A., Kvasnicka, F., Copikova, J., and Park, Y. I. (2010). Structure and antitumor activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida. Carbohydr. Polym. 81, 41-48.

Teruya, T., Konishi, T., Uechi, S., Tamaki, H., and Tako, M. (2007). Anti-proliferative activity of oversulfated fucoidan from commercially cultured Cladosiphon okamuranus TOKIDA in U937 cells. Int. J. Biol. Macromol. 41, 221-226.

Wijesinghe, W. A. J. P., Athukorala, Y., and Jeon, Y. J. (2011). Effect of anticoagulative sulfated polysaccharide purified from enzyme-assistant extract of a brown seaweed Ecklonia cava on Wistar rats. Carbohydr. Polym. 86, 917-921.

Yang, L. and Zhang, L. M. (2009). Chemical structure and chain conformational characterization of some bioactive polysaccharides isolated from natural sources. Carbohydr. Polym. 76, 349-361.

Yang, M., Ma, C., Sun, J., Shao, Q., Gao, W., Zhang, Y., Li, Z., Xie, Q., Dong, Z., and Qu, X. (2008). Fucoidan stimulation induces a functional maturation of human monocyte-derived dendritic cells. Int. Immunopharmacol. 8,1754-1760.

Yarden, Y. and Sliwkowski, M. X. (2001). Untangling the ErbB signaling network. Nat. Rev. Mol. Cell Biol. 2, 127-137.

Yoo, Y. C., Kim, W. J., Kim, S. Y., Kim, S. M., Chung, M. K., Park, J. W., Suh, H. H., Lee, K. B., and Park, Y. I. (2007). Immnomodulating activity of a fucoidan isolated from Korean Undaria pinnatifida sporophyll. Algae 22, 333-338.

Yoon, S. J., Pyun, Y. R., Hwang, J. K., and Mourao, P. A. S. (2007). A sulfated fucan from the brown alga Laminaria cichorioides has mainly heparin cofactor II-dependent anticoagulant activity. Carbohydr. Res. 342, 2326-2330.

Zvyagintseva, T. N., Shevchenko, N. M., Chizhov, A. O., Krupnova, T. N., Sundukova, E. V., and Isakov, V. V. (2003). Water-soluble polysaccharides of some far-eastern brown seaweeds. Distribution, structure and their dependence on the developmental conditions. J. Exp. Mar. Biol. Ecol. 294,1-13.

10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook

Post a comment