The Perspectives of the Application of Biofilm in the Prevention of Chronic Infections

Abdul Bakrudeen Ali Ahmed1 and Rosna Mat Taha

Contents I. Introduction 404

A. Outline of chronic infections 404

II. Mechanism of Action on Biofilms in

Chronic Infection 405

III. Chronic Infection in Human and

Beneficial by Biofilms 408

A. Periodontal diseases 409

B. Wound inflammation 410

C. Kidney relevance 411

D. Diabetic foot ulcer 411

E. Eye infection 412

F. Otolaryngologic diseases 412

G. Immunity 413

IV. Conclusion 413 References 414

Abstract Biofilms are a natural part of the ecology of the earth. Many biofilms are quite harmful and must be treated or controlled. Other biofilms are beneficial and can be used to help fix serious problems. Biofilms can grow on many different surfaces, including rocks in water, foods, teeth, and various biomedical implants. This bacterial colonization may present the need for additional operations, amputation, or it may even lead to death. The fundamental

Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur, Malaysia 1 Corresponding author: Abdul Bakrudeen Ali Ahmed, E-mail address: [email protected]

Advances in Food and Nutrition Research, Volume 64 © 2011 Elsevier Inc.

ISSN 1043-4526, DOI: 10.1016/B978-0-12-387669-0.00031-4 All rights reserved.

principles of bacterial cell attachment and biofilm formation are discussed. Biofilms represents a new, wide-open field practice and research that is only going to get hotter with time. Functional organic plasma polymerized coatings are also discussed for their potential as bio-sensitive interfaces, connecting metallic electronic devices with their physiological environments.

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