Concluding remarks

The wealth of the pharmacological effects and potency of galanin hence make the galanin receptor subtypes promising drug targets (Table 16.4). Continuing efforts in galanin research will likely reveal additional receptor subtypes, and hopefully there will also soon be more specific and potent ligands to the different subtypes. Such ligands could then serve as leads in the development of specific drugs targeted at central as well as peripheral binding sites for galanin. Considering its observed function in various important biological systems, its widespread distribution, and its modulatory effects on other transmitters' actions, these potential drugs could have applications in the treatment of disorders related to obesity, pain, epilepsy, depression, memory impairment, and neurodegeneration.

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