Cognitive and affective disturbances in multiple sclerosis

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Jurg Kesselring and Ulrike Klement

The emotional and relationship problems associated with MS have not always been fully appreciated by the medical profession, which has tended to concentrate on the physical aspects of this disease. Yet the psychological problems of MS often cause more suffering than physical effects.1

Neuropsychological disturbances and psychiatric problems are common in multiple sclerosis (MS).2-7 It is difficult to differentiate which of the disturbances are due to organic disease and which are psychological reactions to a disease which is always an enormous psychological burden, with its unpredictable course and potential to lead to severe disability and handicap.

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