In conclusion, 5-HT2C receptors can exert tonic, phasic and constitutive controls in the brain of mammals. It seems that these activities, when relevant, are not mediated by the same population of 5-HT2C receptors. It is likely that the receptor per se may not fully account for this property and that the activity of the cell carrying the receptor imposes the modality of interaction. From a pathophysiological point of view, changes of cellular activity in a system might favor or displace one modality of interaction to another independently from changes in 5-HT extracellular levels, a hypothesis already proposed (Curzon et al. 1997) with regard to the effects of 5-HT drugs in the control of feeding behavior.

Defeat Drugs and Live Free

Defeat Drugs and Live Free

Being addicted to drugs is a complicated matter condition that's been specified as a disorder that evidences in the obsessional thinking about and utilization of drugs. It's a matter that might continue to get worse and become disastrous and deadly if left untreated.

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