References

Aita VM, Liu J, Knowles JA, et al (1999) A comprehensive linkage analysis of chromosome 21q22 supports prior evidence for a putative bipolar affective disorder locus. Am J Hum Genet 64:210-217.

Amore M, Strippoli P, Laterza C, et al (2004) Sequence analysis of ADARB1 gene in patients with familial bipolar disorder. J Affect Disord 81:79-85.

Bass BL (2002) RNA editing by adenosine deaminases that act on RNA. Annu Rev Biochem 71:817-846.

Berg KA, Clarke WP, Sailstad C, et al (1994) Signal transduction differences between 5-hydroxytryptamine type 2A and type 2C receptor systems. Mol Pharmacol 46:477-484.

Berg KA, Dunlop J, Sanchez T, et al (2008) A conservative, single-amino acid substitution in the second cytoplasmic domain of the human Serotonin2C receptor alters both ligand-dependent and -independent receptor signaling. J Pharmacol Exp Ther 324:1084-1092.

Bhansali P, Dunning J, Singer SE, et al (2007) Early life stress alters adult serotonin 2C receptor pre-mRNA editing and expression of the alpha subunit of the heterotrimeric G-protein G q. J Neurosci 27:1467-1473.

Burns CM, Chu H, Rueter SM, et al (1997) Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature 387:303-308.

Castensson A, Emilsson L, Sundberg R, et al (2003) Decrease of serotonin receptor 2C in schizophrenia brains identified by high-resolution mRNA expression analysis. Biol Psychiatry 54:1212-1221.

Cavaille J, Buiting K, Kiefmann M, et al (2000) Identification of brain-specific and imprinted small nucleolar RNA genes exhibiting an unusual genomic organization. Proc Natl Acad Sci U S A 97:14311-14316.

Chen CX, Cho DS, Wang Q, et al (2000) A third member of the RNA-specific adenosine deaminase gene family, ADAR3, contains both single- and double-stranded RNA binding domains. RNA 6:755-767.

Detera-Wadleigh SD, Badner JA, Goldin LR, et al (1996) Affected-sib-pair analyses reveal support of prior evidence for a susceptibility locus for bipolar disorder, on 21q. Am J Hum Genet 58:1279-1285.

Dracheva S, Elhakem SL, Marcus SM, et al (2003) RNA editing and alternative splicing of human serotonin 2C receptor in schizophrenia. J Neurochem 87:1402-1412.

Dracheva S, Patel N, Woo DA, et al (2008a) Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide. Mol Psychiatry 13:1001-1010.

Dracheva S, Chin B, and Haroutunian V (2008b) Altered serotonin 2C receptor RNA splicing in suicide: association with editing. Neuroreport 19:379-382.

Du Y, Davisson MT, Kafadar K, et al (2006) A-to-I pre-mRNA editing of the serotonin 2C receptor: comparisons among inbred mouse strains. Gene 382:39-46.

Du Y, Stasko M, Costa AC, et al (2007) Editing of the serotonin 2C receptor pre-mRNA: Effects of the Morris Water Maze. Gene 391:186-197.

Englander MT, Dulawa SC, Bhansali P, et al (2005) How stress and fluoxetine modulate serotonin 2C receptor pre-mRNA editing. J Neurosci 25:648-651.

Flomen R, Knight J, Sham P, et al (2004) Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene. Nucleic Acids Res 32:2113-2122.

Gurevich I, Tamir H, Arango V, et al (2002a) Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims. Neuron 34:349-356.

Gurevich I, Englander MT, Adlersberg M, et al (2002b) Modulation of serotonin 2C receptor editing by sustained changes in serotonergic neurotransmission. J Neurosci 22:10529-10532.

Hackler EA, Airey DC, Shannon CC, et al (2006) 5-HT(2C) receptor RNA editing in the amygdala of C57BL/6J, DBA/2J, and BALB/cJ mice. Neurosci Res 55:96-104.

Hartner JC, Schmittwolf C, Kispert A, et al (2004) Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1. J Biol Chem 279:4894-4902.

Heisler LK, Zhou L, Bajwa P, et al (2007) Serotonin 5-HT(2C) receptors regulate anxiety-like behavior. Genes Brain Behav 6:491-496.

Higuchi M, Maas S, Single FN, et al (2000) Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature 406:78-81.

Iwamoto K and Kato T (2002) Effects of cocaine and reserpine administration on RNA editing of rat 5-HT2C receptor estimated by primer extension combined with denaturing high-performance liquid chromatography. Pharmacogenomics J 2:335-340.

Iwamoto K and Kato T (2003) RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders. Neurosci Lett 346:169-172.

Iwamoto K, Kakiuchi C, Bundo M, et al (2004) Molecular characterization of bipolar disorder by comparing gene expression profiles of postmortem brains of major mental disorders. Mol Psychiatry 9:406-416.

Iwamoto K, Nakatani N, Bundo M, et al (2005) Altered RNA editing of serotonin 2C receptor in a rat model of depression. Neurosci Res 53:69-76.

Iwamoto K, Bundo M, and Kato T (2009) Serotonin receptor 2C and mental disorders: genetic, expression and RNA editing studies. RNA Biol 6:248-253.

Kawahara Y, Grimberg A, Teegarden S, et al (2008) Dysregulated editing of serotonin 2C receptor mRNAs results in energy dissipation and loss of fat mass. J Neurosci 28:12834-12844.

Keegan LP, Gallo A, and O'Connell MA (2001) The many roles of an RNA editor. Nat Rev Genet 2:869-878.

Kishore S and Stamm S (2006) The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C. Science 311:230-232.

Kostyrko A, Hauser J, Rybakowski JK, et al (2006) Screening of chromosomal region 21q22.3 for mutations in genes associated with neuronal Ca2+ signalling in bipolar affective disorder. Acta Biochim Pol 53:317-320.

Lerer B, Macciardi F, Segman RH, et al (2001) Variability of 5-HT2C receptor cys23ser polymorphism among European populations and vulnerability to affective disorder. Mol Psychiatry 6:579-585.

Liu Y, Emeson RB, and Samuel CE (1999) Serotonin-2C receptor pre-mRNA editing in rat brain and in vitro by splice site variants of the interferon-inducible double-stranded RNA-specific adenosine deaminase ADAR1. J Biol Chem 274:18351-18358.

Maas S, Rich A, and Nishikura K (2003) A-to-I RNA editing: recent news and residual mysteries. J Biol Chem 278:1391-1394.

Marion S, Weiner DM, and Caron MG (2004) RNA editing induces variation in desensitization and trafficking of 5-hydroxytryptamine 2c receptor isoforms. J Biol Chem 279:2945-2954.

Massat I, Lerer B, Souery D, et al (2007) HTR2C (cys23ser) polymorphism influences early onset in bipolar patients in a large European multicenter association study. Mol Psychiatry 12:797-798.

McGrew L, Chang MS, and Sanders-Bush E (2002) Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Galpha13 and pertussis toxin-insensitive Gbetagamma subunits. Mol Pharmacol 62:1339-1343.

Melcher T, Maas S, Herb A, et al (1996) A mammalian RNA editing enzyme. Nature 379:460-464.

Miyamura Y, Suzuki T, Kono M, et al (2003) Mutations of the RNA-specific adenosine deaminase gene (DSRAD) are involved in dyschromatosis symmetrica hereditaria. Am J Hum Genet 73:693-699.

Nakatani N, Aburatani H, Nishimura K, et al (2004) Comprehensive expression analysis of a rat depression model. Pharmacogenomics J 4:114-126.

Navaratnam N and Sarwar R (2006) An overview of cytidine deaminases. Int J Hematol 83:195-200.

Nishikura K (2006) Editor meets silencer: crosstalk between RNA editing and RNA interference. Nat Rev Mol Cell Biol 7:919-931.

Niswender CM, Copeland SC, Herrick-Davis K, et al (1999) RNA editing of the human serotonin 5-hydroxytryptamine 2C receptor silences constitutive activity. J Biol Chem 274:9472-9478.

Niswender CM, Herrick-Davis K, Dilley GE, et al (2001) RNA editing of the human serotonin 5-HT2C receptor. alterations in suicide and implications for serotonergic pharmacotherapy. Neuropsychopharmacology 24:478-491.

Overmier JB and Seligman ME (1967) Effects of inescapable shock upon subsequent escape and avoidance responding. J Comp Physiol Psychol 63:28-33.

Patterson JB and Samuel CE (1995) Expression and regulation by interferon of a double-stranded-RNA-specific adenosine deaminase from human cells: evidence for two forms of the deaminase. Mol Cell Biol 15:5376-5388.

Rocha BA, Goulding EH, O'Dell LE, et al (2002) Enhanced locomotor, reinforcing, and neuro-chemical effects of cocaine in serotonin 5-hydroxytryptamine 2C receptor mutant mice. J Neurosci 22:10039-10045.

Schaefer M, Engelbrecht MA, Gut O, et al (2002) Interferon alpha (IFNalpha) and psychiatric syndromes: a review. Prog Neuropsychopharmacol Biol Psychiatry 26:731-746.

Sodhi MS, Burnet PW, Makoff AJ, et al (2001) RNA editing of the 5-HT(2C) receptor is reduced in schizophrenia. Mol Psychiatry 6:373-379.

Sodhi MS, Airey DC, Lambert W, et al (2005) A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts. Mol Pharmacol 68:711-719.

Tecott LH, Sun LM, Akana SF, et al (1995) Eating disorder and epilepsy in mice lacking 5-HT2c serotonin receptors. Nature 374:542-546.

Telner JI and Singhal RL (1984) Psychiatric progress. The learned helplessness model of depression. J Psychiatr Res 18:207-215.

Vitali P, Basyuk E, Le Meur E, et al (2005) ADAR2-mediated editing of RNA substrates in the nucleolus is inhibited by C/D small nucleolar RNAs. J Cell Biol 169:745-753.

Werry TD, Gregory KJ, Sexton PM, et al (2005) Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2. J Neurochem 93:1603-1615.

Yang W, Wang Q, Kanes SJ, et al (2004) Altered RNA editing of serotonin 5-HT2C receptor induced by interferon: implications for depression associated with cytokine therapy. Brain Res Mol Brain Res 124:70-78.

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