"Po = intrinsic permeability, SD = estimated standard deviation. bPu = unstirred water permeability. cData range actually used in the regression analysis. ''Number of Pe measurements.

eGOF = goodness of fit in the weighted nonlinear regression analysis.

^Carbamazepine, antipyrine, terbutaline, and hydrochlorothiazide were treated as neutral molecules. Their effective permeabilities were corrected for the unstirred water layer using estimated unstirred water layer permeabilities, determined by the other molecules of similar lipophilicities and size.

TABLE 7.18 Interpolated Apparent and Membrane Permeabilities Determined from Double-Sink Conditions: 20% Soy Lecithin in Dodecane
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