Ref. 82


Refs. 97,611

Figure 7.64 Human intestinal absorption compared to Caco-2 permeabilities from several groups.

Yazdanian's group [602], which seem to be marginally better than those of most of the other groups. Griseofulvin is a false positive outlier, which can be rationalized by recognizing that very low solubility of the molecule may be responsible for the low HIA value. The other outlier is nadolol, which has good aqueous s £

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