Oxidative Damage to Macromolecules

Free radicals are important because they can damage cells. This capacity lies in their ability to alter biological molecules. The types of modifications caused by such radicals pose a risk to cellular homeostasis and could provoke the death of an individual cell and eventually an organism. All molecules are more or less sensitive to oxidation; however, the effect is different depending on the type of molecule affected, the role ofsuch a molecule in cellular physiology, the existence ofrepair mechanisms and the possibility of a removal of toxic products.

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