Anxiety is a very common concomitant condition in patients with chronic pain, presenting as panic, PTSD, obsessive/compulsive disorder (OCD), etc. Although anxiolytics do not possess intrinsic analgesic activity, anxiety is often accompanied by somatic complaints of chest pain, GI upset, or neurologic symptoms such as dysesthesias, headache, which may be relieved by anxiolysis. Benzodiazepines are also a mainstay in the treatment of restless legs syndrome (RLS). Although most RLS studies were conducted with clonazepam, current recommendations focus on shorter acting benzodiazepines such as triazolam (Silber et al. 2004).
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